Zinc in PDB 4c4a: Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah

All present enzymatic activity of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah:
2.1.1.125; 2.1.1.126;

The structure of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah, PDB code: 4c4a was solved by V.Cura, N.Troffer-Charlier, L.Bonnefond, J.M.Wurtz, J.Cavarelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.353 / 1.70
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	97.322, 97.322, 168.754, 90.00, 90.00, 90.00
R / Rfree (%)	15.97 / 18.97

The binding sites of Zinc atom in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah (pdb code 4c4a). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah, PDB code: 4c4a:

Zinc binding site 1 out of 1 in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with Sah within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn4692 b:27.7 occ:1.00 ND1 A:HIS371 2.1 24.8 1.0 SG A:CYS366 2.3 28.3 1.0 SG A:CYS219 2.3 28.4 1.0 SG A:CYS368 2.3 28.1 1.0 CE1 A:HIS371 3.0 29.8 1.0 CG A:HIS371 3.3 28.4 1.0 CB A:CYS219 3.3 31.5 1.0 CB A:CYS366 3.3 27.0 1.0 CB A:CYS368 3.4 26.4 1.0 N A:CYS368 3.6 27.1 1.0 CB A:HIS371 3.7 26.9 1.0 CA A:CYS366 3.7 28.6 1.0 N A:HIS371 3.9 23.9 1.0 CA A:CYS368 4.0 26.9 1.0 N A:ASP367 4.0 29.8 1.0 NE2 A:HIS371 4.2 27.6 1.0 C A:CYS366 4.2 30.4 1.0 N A:GLN369 4.3 29.5 1.0 CD2 A:HIS371 4.3 23.4 1.0 C A:CYS368 4.4 27.2 1.0 N A:ALA370 4.4 26.0 1.0 CA A:HIS371 4.4 25.7 1.0 CA A:GLY221 4.5 27.7 1.0 N A:GLY221 4.6 29.5 1.0 C A:ASP367 4.7 37.2 1.0 CA A:CYS219 4.7 31.6 1.0 C A:GLY221 4.8 35.4 1.0 C A:ALA370 4.9 23.0 1.0 C A:GLN369 4.9 31.1 1.0 CA A:ASP367 5.0 31.8 1.0 O A:GLY221 5.0 31.3 1.0 CA A:ALA370 5.0 24.1 1.0

V.Cura, N.Troffer-Charlier, J.M.Wurtz, L.Bonnefond, J.Cavarelli. Structural Insight Into Arginine Methylation By the Mouse Protein Arginine Methyltransferase 7: A Zinc Finger Freezes the Mimic of the Dimeric State Into A Single Active Site. Acta Crystallogr.,Sect.D V. 70 2401 2014.
ISSN: ISSN 0907-4449
PubMed: 25195753
DOI: 10.1107/S1399004714014278