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Atomistry » Zinc » PDB 4bis-4bu9 » 4bjc » |
Zinc in PDB 4bjc: Crystal Structure of Human Tankyrase 2 in Complex with RucaparibEnzymatic activity of Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib
All present enzymatic activity of Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib:
2.4.2.30; Protein crystallography data
The structure of Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib, PDB code: 4bjc
was solved by
T.Haikarainen,
M.Narwal,
L.Lehtio,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4bjc:
The structure of Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib
(pdb code 4bjc). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib, PDB code: 4bjc: Zinc binding site 1 out of 1 in 4bjcGo back to Zinc Binding Sites List in 4bjc
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib
Mono view Stereo pair view
Reference:
T.Haikarainen,
M.Narwal,
P.Joensuu,
L.Lehtio.
Evaluation and Structural Basis For the Inhibition of Tankyrases By Parp Inhibitors Acs Med.Chem.Lett. V. 5 18 2014.
Page generated: Wed Dec 16 05:05:23 2020
ISSN: ISSN 1948-5875 PubMed: 24900770 DOI: 10.1021/ML400292S |
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