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Atomistry » Zinc » PDB 4b3s-4bin » 4bhi » |
Zinc in PDB 4bhi: Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)PropanoateEnzymatic activity of Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate
All present enzymatic activity of Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate:
1.14.11.1; Protein crystallography data
The structure of Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate, PDB code: 4bhi
was solved by
K.Tars,
J.Leitans,
A.Kazaks,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate
(pdb code 4bhi). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate, PDB code: 4bhi: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4bhiGo back to Zinc Binding Sites List in 4bhi
Zinc binding site 1 out
of 2 in the Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4bhiGo back to Zinc Binding Sites List in 4bhi
Zinc binding site 2 out
of 2 in the Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1,1,1,2-Tetramethylhydrazin-1-Ium-2-Yl)Propanoate
Mono view Stereo pair view
Reference:
K.Tars,
J.Leitans,
A.Kazaks,
D.Zelencova,
E.Liepinsh,
J.Kuka,
M.Makrecka,
D.Lola,
V.Andrianovs,
D.Gustina,
S.Grinberga,
E.Liepinsh,
I.Kalvinsh,
M.Dambrova,
E.Loza,
O.Pugovics.
Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem. V. 57 2213 2014.
Page generated: Sat Oct 26 19:47:30 2024
ISSN: ISSN 0022-2623 PubMed: 24571165 DOI: 10.1021/JM401603E |
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