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Atomistry » Zinc » PDB 4b3s-4bin » 4bf6 » |
Zinc in PDB 4bf6: Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-SulfonamideEnzymatic activity of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide
All present enzymatic activity of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide:
4.2.1.1; Protein crystallography data
The structure of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide, PDB code: 4bf6
was solved by
K.Tars,
J.Leitans,
R.Zalubovskis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide
(pdb code 4bf6). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide, PDB code: 4bf6: Zinc binding site 1 out of 1 in 4bf6Go back to Zinc Binding Sites List in 4bf6
Zinc binding site 1 out
of 1 in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-Triazol-4-Yl) Thiophene-2-Sulfonamide
Mono view Stereo pair view
Reference:
J.Leitans,
A.Sprudza,
M.Tanc,
I.Vozny,
R.Zalubovskis,
K.Tars,
C.T.Supuran.
5-Substituted-(1,2,3-Triazol-4-Yl)Thiophene-2-Sulfonamides Strongly Inhibit Human Carbonic Anhydrases I, II, IX and XII: Solution and X-Ray Crystallographic Studies. Bioorg.Med.Chem. V. 21 5130 2013.
Page generated: Sat Oct 26 19:42:40 2024
ISSN: ISSN 0968-0896 PubMed: 23859774 DOI: 10.1016/J.BMC.2013.06.041 |
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