Zinc in PDB 4bac: Prototype Foamy Virus Strand Transfer Complexes on Product Dna

All present enzymatic activity of Prototype Foamy Virus Strand Transfer Complexes on Product Dna:
2.7.7.49; 2.7.7.7; 3.1.26.13;

The structure of Prototype Foamy Virus Strand Transfer Complexes on Product Dna, PDB code: 4bac was solved by Z.Yin, M.Lapkouski, W.Yang, R.Craigie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.14 / 3.26
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	160.617, 160.617, 125.092, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.6

The structure of Prototype Foamy Virus Strand Transfer Complexes on Product Dna also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the Prototype Foamy Virus Strand Transfer Complexes on Product Dna (pdb code 4bac). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Prototype Foamy Virus Strand Transfer Complexes on Product Dna, PDB code: 4bac:

Zinc binding site 1 out of 1 in the Prototype Foamy Virus Strand Transfer Complexes on Product Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Prototype Foamy Virus Strand Transfer Complexes on Product Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1376 b:56.3 occ:1.00 SG A:CYS99 1.5 55.5 1.0 NE2 A:HIS62 2.1 45.6 1.0 ND1 A:HIS66 2.4 51.8 1.0 CE1 A:HIS62 2.9 43.6 1.0 SG A:CYS96 2.9 52.9 1.0 CB A:CYS99 3.1 52.3 1.0 CG A:HIS66 3.2 48.9 1.0 CB A:HIS66 3.2 47.3 1.0 CD2 A:HIS62 3.2 43.5 1.0 CE1 A:HIS66 3.5 50.7 1.0 CA A:HIS66 3.7 47.1 1.0 CB A:CYS96 3.8 51.4 1.0 CA A:CYS99 4.0 52.0 1.0 ND1 A:HIS62 4.0 44.1 1.0 N A:CYS99 4.0 51.6 1.0 C A:HIS66 4.2 46.7 1.0 CG A:HIS62 4.2 44.3 1.0 CD2 A:HIS66 4.4 49.8 1.0 O A:HIS66 4.5 46.9 1.0 NE2 A:HIS66 4.6 50.4 1.0 N A:THR67 4.9 46.4 1.0 C A:GLN98 4.9 51.2 1.0 N A:HIS66 5.0 46.8 1.0

Z.Yin, M.Lapkouski, W.Yang, R.Craigie. Assembly of Prototype Foamy Virus Strand Transfer Complexes on Product Dna Bypassing Catalysis of Integration. Protein Sci. V. 21 1849 2012.
ISSN: ISSN 0961-8368
PubMed: 23011895
DOI: 10.1002/PRO.2166