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Zinc in PDB 4ay2: Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I

Enzymatic activity of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I

All present enzymatic activity of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I:
3.6.4.13;

Protein crystallography data

The structure of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I, PDB code: 4ay2 was solved by D.Luo, A.M.Pyle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.90 / 2.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 47.745, 76.156, 221.222, 90.00, 90.00, 90.00
R / Rfree (%) 21.816 / 28.583

Other elements in 4ay2:

The structure of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I (pdb code 4ay2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I, PDB code: 4ay2:

Zinc binding site 1 out of 1 in 4ay2

Go back to Zinc Binding Sites List in 4ay2
Zinc binding site 1 out of 1 in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1923

b:84.8
occ:1.00
SG A:CYS813 2.2 86.4 1.0
SG A:CYS810 2.3 74.3 1.0
SG A:CYS864 2.3 73.9 1.0
SG A:CYS869 2.6 81.6 1.0
CB A:CYS810 3.0 70.8 1.0
CB A:CYS864 3.1 71.6 1.0
CB A:CYS869 3.2 88.3 1.0
CB A:CYS813 3.8 92.3 1.0
N A:CYS813 4.0 86.8 1.0
CA A:CYS813 4.4 90.4 1.0
CB A:ARG866 4.5 91.4 1.0
CA A:CYS810 4.5 68.4 1.0
CG A:ARG866 4.5 89.5 1.0
CA A:CYS864 4.6 70.2 1.0
NE1 A:TRP873 4.6 62.8 1.0
CA A:CYS869 4.7 94.0 1.0
CZ2 A:TRP873 4.7 63.3 1.0
CB A:HIS871 4.8 73.6 1.0
CB A:LYS812 4.8 85.4 1.0
O A:CYS810 4.9 75.4 1.0
C A:CYS813 5.0 88.2 1.0
C A:CYS810 5.0 71.7 1.0
CB A:ALA815 5.0 79.3 1.0

Reference:

D.Luo, A.Kohlway, A.Vela, A.M.Pyle. Visualizing the Determinants of Viral Rna Recognition By Innate Immune Sensor Rig-I. Structure V. 20 1983 2012.
ISSN: ISSN 0969-2126
PubMed: 23022350
DOI: 10.1016/J.STR.2012.08.029
Page generated: Wed Dec 16 05:04:16 2020

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