Zinc in PDB 4ay2: Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I

All present enzymatic activity of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I:
3.6.4.13;

The structure of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I, PDB code: 4ay2 was solved by D.Luo, A.M.Pyle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.90 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	47.745, 76.156, 221.222, 90.00, 90.00, 90.00
R / Rfree (%)	21.816 / 28.583

The structure of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I (pdb code 4ay2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I, PDB code: 4ay2:

Zinc binding site 1 out of 1 in the Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Capturing 5' Tri-Phosphorylated Rna Duplex By Rig-I within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1923 b:84.8 occ:1.00 SG A:CYS813 2.2 86.4 1.0 SG A:CYS810 2.3 74.3 1.0 SG A:CYS864 2.3 73.9 1.0 SG A:CYS869 2.6 81.6 1.0 CB A:CYS810 3.0 70.8 1.0 CB A:CYS864 3.1 71.6 1.0 CB A:CYS869 3.2 88.3 1.0 CB A:CYS813 3.8 92.3 1.0 N A:CYS813 4.0 86.8 1.0 CA A:CYS813 4.4 90.4 1.0 CB A:ARG866 4.5 91.4 1.0 CA A:CYS810 4.5 68.4 1.0 CG A:ARG866 4.5 89.5 1.0 CA A:CYS864 4.6 70.2 1.0 NE1 A:TRP873 4.6 62.8 1.0 CA A:CYS869 4.7 94.0 1.0 CZ2 A:TRP873 4.7 63.3 1.0 CB A:HIS871 4.8 73.6 1.0 CB A:LYS812 4.8 85.4 1.0 O A:CYS810 4.9 75.4 1.0 C A:CYS813 5.0 88.2 1.0 C A:CYS810 5.0 71.7 1.0 CB A:ALA815 5.0 79.3 1.0

D.Luo, A.Kohlway, A.Vela, A.M.Pyle. Visualizing the Determinants of Viral Rna Recognition By Innate Immune Sensor Rig-I. Structure V. 20 1983 2012.
ISSN: ISSN 0969-2126
PubMed: 23022350
DOI: 10.1016/J.STR.2012.08.029