Zinc in PDB 4asq: Crystal Structure of Ance in Complex with Bradykinin

All present enzymatic activity of Crystal Structure of Ance in Complex with Bradykinin:
3.4.15.1;

The structure of Crystal Structure of Ance in Complex with Bradykinin, PDB code: 4asq was solved by M.Akif, G.Masuyer, E.D.Sturrock, R.E.Isaac, K.R.Acharya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.56 / 1.99
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	173.125, 173.125, 101.673, 90.00, 90.00, 120.00
R / Rfree (%)	18.035 / 19.987

The binding sites of Zinc atom in the Crystal Structure of Ance in Complex with Bradykinin (pdb code 4asq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Ance in Complex with Bradykinin, PDB code: 4asq:

Zinc binding site 1 out of 1 in the Crystal Structure of Ance in Complex with Bradykinin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Ance in Complex with Bradykinin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1615 b:24.6 occ:1.00 OE1 A:GLU395 2.0 22.9 1.0 NE2 A:HIS367 2.1 24.7 1.0 NE2 A:HIS371 2.1 22.9 1.0 N P:ARG1 2.1 30.5 1.0 O P:ARG1 2.5 30.2 1.0 C P:ARG1 2.9 30.2 1.0 CD A:GLU395 2.9 22.5 1.0 CD2 A:HIS367 3.0 25.1 1.0 CE1 A:HIS371 3.0 23.0 1.0 CA P:ARG1 3.0 30.5 1.0 CE1 A:HIS367 3.1 24.4 1.0 CD2 A:HIS371 3.1 22.8 1.0 OE2 A:GLU395 3.2 22.7 1.0 OE2 A:GLU368 3.8 28.8 1.0 N P:PRO2 4.0 29.8 1.0 OG2 A:FLC1624 4.0 55.5 1.0 O A:HOH2373 4.1 30.6 1.0 ND1 A:HIS367 4.1 24.6 1.0 ND1 A:HIS371 4.1 23.1 1.0 CG A:HIS367 4.2 25.1 1.0 CG A:HIS371 4.2 23.6 1.0 CB P:ARG1 4.2 30.7 1.0 OH A:TYR507 4.3 22.1 1.0 CG A:GLU395 4.3 22.2 1.0 CE1 A:TYR507 4.5 20.5 1.0 CA A:GLU395 4.6 22.4 1.0 CA P:PRO2 4.6 29.6 1.0 CB A:GLU395 4.7 22.0 1.0 CD A:GLU368 4.7 28.0 1.0 CZ A:TYR507 4.9 20.7 1.0 OE1 A:GLU368 4.9 28.5 1.0 CGC A:FLC1624 4.9 55.9 1.0

M.Akif, G.Masuyer, R.J.Bingham, E.D.Sturrock, R.E.Isaac, K.R.Acharya. Structural Basis of Peptide Recognition By the Angiotensin-I Converting Enzyme Homologue Ance From Drosophila Melanogaster Febs J. V. 279 4525 2012.
ISSN: ISSN 1742-464X
PubMed: 23082758
DOI: 10.1111/FEBS.12038