Zinc in PDB 4a0i: Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1

The structure of Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1, PDB code: 4a0i was solved by A.A.Jeyaprakash, C.Basquin, U.Jayachandran, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.066 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	113.650, 70.514, 82.382, 90.00, 131.80, 90.00
R / Rfree (%)	20.42 / 25.22

The binding sites of Zinc atom in the Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1 (pdb code 4a0i). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1, PDB code: 4a0i:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:77.3 occ:1.00 NE2 A:HIS77 2.2 93.3 1.0 SG A:CYS57 2.2 74.7 1.0 SG A:CYS84 2.3 95.3 1.0 SG A:CYS60 2.4 89.5 1.0 CE1 A:HIS77 2.6 73.0 1.0 CB A:CYS57 3.0 65.2 1.0 CB A:CYS84 3.0 78.4 1.0 CB A:CYS60 3.1 72.2 1.0 N A:CYS60 3.5 79.5 1.0 CD2 A:HIS77 3.5 1.0 1.0 CA A:CYS60 3.9 72.4 1.0 ND1 A:HIS77 3.9 86.0 1.0 CG A:HIS77 4.4 0.1 1.0 CA A:CYS84 4.4 0.3 1.0 CA A:CYS57 4.5 70.8 1.0 C A:PHE59 4.6 78.2 1.0 C A:CYS60 4.6 88.0 1.0 CB A:PHE59 4.7 64.6 1.0 OG A:SER81 4.7 0.2 1.0 CB A:SER81 4.8 98.5 1.0 N A:PHE61 4.8 85.0 1.0 N A:PHE59 4.9 78.7 1.0 CA A:PHE59 4.9 77.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Survivin Bound to the N-Terminal Tail of HSGO1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn801 b:69.8 occ:1.00 NE2 B:HIS77 2.2 82.8 1.0 SG B:CYS84 2.2 86.0 1.0 SG B:CYS57 2.3 63.9 1.0 SG B:CYS60 2.5 84.5 1.0 CE1 B:HIS77 2.6 69.9 1.0 CB B:CYS57 3.0 65.3 1.0 CB B:CYS60 3.0 58.8 1.0 CB B:CYS84 3.1 72.1 1.0 N B:CYS60 3.5 78.4 1.0 CD2 B:HIS77 3.5 98.9 1.0 CA B:CYS60 3.8 73.3 1.0 ND1 B:HIS77 3.9 79.4 1.0 CG B:HIS77 4.4 97.3 1.0 CA B:CYS84 4.4 97.5 1.0 CA B:CYS57 4.4 73.7 1.0 C B:PHE59 4.6 73.8 1.0 C B:CYS60 4.6 78.0 1.0 CB B:PHE59 4.7 53.8 1.0 OG B:SER81 4.7 0.9 1.0 N B:PHE61 4.8 77.5 1.0 CB B:SER81 4.8 97.3 1.0 N B:PHE59 4.9 61.9 1.0 CA B:PHE59 4.9 76.6 1.0

A.A.Jeyaprakash, C.Basquin, U.Jayachandran, E.Conti. Structural Basis For the Recognition of Phosphorylated Histone H3 By the Survivin Subunit of the Chromosomal Passenger Complex. Structure V. 19 1625 2011.
ISSN: ISSN 0969-2126
PubMed: 22032967
DOI: 10.1016/J.STR.2011.09.002