Zinc in PDB 3sip: Crystal Structure of Drice and DIAP1-BIR1 Complex

The structure of Crystal Structure of Drice and DIAP1-BIR1 Complex, PDB code: 3sip was solved by X.Li, J.Wang, Y.Shi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.09 / 3.50
Space group	I 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	91.350, 148.115, 156.738, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 25.6

The binding sites of Zinc atom in the Crystal Structure of Drice and DIAP1-BIR1 Complex (pdb code 3sip). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Drice and DIAP1-BIR1 Complex, PDB code: 3sip:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Drice and DIAP1-BIR1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Drice and DIAP1-BIR1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn1 b:1.0 occ:1.00 NE2 E:HIS100 2.1 0.2 1.0 SG E:CYS83 2.3 91.7 1.0 SG E:CYS107 2.3 78.2 1.0 SG E:CYS80 2.3 0.8 1.0 CE1 E:HIS100 2.8 0.2 1.0 CB E:CYS107 3.0 90.2 1.0 CB E:CYS80 3.2 98.4 1.0 CD2 E:HIS100 3.3 0.8 1.0 CB E:CYS83 3.6 0.2 1.0 ND1 E:HIS100 4.0 91.7 1.0 N E:CYS83 4.2 0.5 1.0 CA E:CYS107 4.2 94.0 1.0 CG E:HIS100 4.3 95.5 1.0 C E:PHE82 4.4 0.0 1.0 OG E:SER104 4.4 88.7 1.0 CG1 E:VAL85 4.5 0.7 1.0 CA E:CYS83 4.5 0.9 1.0 CB E:PHE82 4.6 0.1 1.0 CA E:CYS80 4.6 0.2 1.0 O E:PHE82 4.8 0.4 1.0 CB E:SER104 4.8 85.0 1.0 CD1 E:LEU110 4.8 96.2 1.0 CA E:PHE82 4.9 0.9 1.0 N E:PHE82 4.9 98.5 1.0 CG E:LEU110 4.9 90.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Drice and DIAP1-BIR1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Drice and DIAP1-BIR1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn1 b:90.3 occ:1.00 NE2 F:HIS100 2.1 100.0 1.0 SG F:CYS83 2.3 92.2 1.0 SG F:CYS80 2.3 0.3 1.0 SG F:CYS107 2.4 89.7 1.0 CE1 F:HIS100 2.7 99.0 1.0 CB F:CYS107 3.0 95.2 1.0 CB F:CYS80 3.1 0.1 1.0 CD2 F:HIS100 3.3 0.9 1.0 CB F:CYS83 3.6 96.9 1.0 ND1 F:HIS100 4.0 93.6 1.0 N F:CYS83 4.2 0.7 1.0 CA F:CYS107 4.3 92.6 1.0 CG F:HIS100 4.3 95.8 1.0 CG1 F:VAL85 4.4 0.0 1.0 OG F:SER104 4.4 84.8 1.0 C F:PHE82 4.4 0.1 1.0 CA F:CYS83 4.5 0.9 1.0 CA F:CYS80 4.6 0.5 1.0 CB F:PHE82 4.6 0.3 1.0 O F:PHE82 4.8 0.6 1.0 CB F:SER104 4.8 79.6 1.0 CD1 F:LEU110 4.8 89.5 1.0 CA F:PHE82 4.9 0.4 1.0 N F:PHE82 4.9 0.2 1.0 CG F:LEU110 4.9 86.8 1.0

X.Li, J.Wang, Y.Shi. Structural Mechanisms of DIAP1 Auto-Inhibition and DIAP1-Mediated Inhibition of Drice. Nat Commun V. 2 408 2011.
ISSN: ESSN 2041-1723
PubMed: 21811237
DOI: 10.1038/NCOMMS1418