Atomistry » Zinc » PDB 3sci-3sjb » 3sd9
Atomistry »
  Zinc »
    PDB 3sci-3sjb »
      3sd9 »

Zinc in PDB 3sd9: Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases

Enzymatic activity of Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases

All present enzymatic activity of Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases, PDB code: 3sd9 was solved by F.Fonseca, M.J.Saavedra, A.Correia, J.Spencer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 72.19 / 1.83
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 32.965, 86.412, 72.193, 90.00, 90.07, 90.00
R / Rfree (%) 18.3 / 21.3

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases (pdb code 3sd9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases, PDB code: 3sd9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3sd9

Go back to Zinc Binding Sites List in 3sd9
Zinc binding site 1 out of 2 in the Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2

b:20.4
occ:1.00
 OD2 A:ASP120 2.0 11.9 1.0
NE2 A:HIS263 2.0 11.9 1.0
O A:HOH317 2.2 18.4 1.0
SG A:CYS221 2.4 10.6 1.0
CE1 A:HIS263 2.8 11.0 1.0
CG A:ASP120 3.0 9.8 1.0
CD2 A:HIS263 3.1 12.2 1.0
CB A:CYS221 3.3 9.6 1.0
OD1 A:ASP120 3.3 10.9 1.0
O A:HOH276 3.5 14.2 1.0
NH2 A:ARG121 3.8 8.5 1.0
ND1 A:HIS263 4.0 11.7 1.0
CG A:HIS263 4.2 11.4 1.0
CB A:ASP120 4.3 7.4 1.0
CA A:CYS221 4.3 9.4 1.0
NE2 A:HIS196 4.4 14.0 1.0
CZ A:ARG121 4.4 9.9 1.0
NE A:ARG121 4.5 10.8 1.0
CE1 A:HIS196 4.8 13.9 1.0
N A:CYS221 5.0 9.1 1.0

Zinc binding site 2 out of 2 in 3sd9

Go back to Zinc Binding Sites List in 3sd9
Zinc binding site 2 out of 2 in the Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Serratia Fonticola Sfh-I: Source of the Nucleophile in the Catalytic Mechanism of Mono-Zinc Metallo-Beta- Lactamases within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1

b:20.7
occ:1.00
 OD2 B:ASP120 1.9 10.5 1.0
NE2 B:HIS263 2.1 9.8 1.0
O B:HOH405 2.3 20.6 1.0
SG B:CYS221 2.4 13.3 1.0
CG B:ASP120 2.9 8.2 1.0
CE1 B:HIS263 3.0 9.6 1.0
CD2 B:HIS263 3.2 9.6 1.0
OD1 B:ASP120 3.2 10.4 1.0
CB B:CYS221 3.3 13.1 1.0
O B:HOH277 3.4 14.8 1.0
NH2 B:ARG121 3.9 11.3 1.0
ND1 B:HIS263 4.1 11.4 1.0
CG B:HIS263 4.3 10.8 1.0
CB B:ASP120 4.3 5.9 1.0
CA B:CYS221 4.4 12.8 1.0
NE2 B:HIS196 4.4 13.9 1.0
CZ B:ARG121 4.5 11.2 1.0
NE B:ARG121 4.5 10.1 1.0
O B:HOH364 4.6 26.4 1.0
O B:HOH396 4.7 19.3 1.0
O B:HOH384 4.8 30.0 1.0
CE1 B:HIS196 4.9 12.9 1.0

Reference:

F.Fonseca, E.H.C.Bromley, M.J.Saavedra, A.Correia, J.Spencer. Crystal Structure of Serratia Fonticola Sfh-I: Activation of the Nucleophile in Mono-Zinc Metallo-Beta-Lactamases To Be Published 2011.
Page generated: Sat Oct 26 15:43:04 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy