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Atomistry » Zinc » PDB 3oxf-3p3h » 3p0n | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3oxf-3p3h » 3p0n » |
Zinc in PDB 3p0n: Human Tankyrase 2 - Catalytic Parp Domain in Complex with An InhibitorEnzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
All present enzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor:
2.4.2.30; Protein crystallography data
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0n
was solved by
T.Karlberg,
M.I.Siponen,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Kotenyova,
E.Kouznetsova,
M.Moche,
P.Nordlund,
T.Nyman,
C.Persson,
P.Schutz,
A.Sehic,
A.G.Thorsell,
L.Tresaugues,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Welin,
H.Schuler,
Structural Genomicsconsortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3p0n:
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
(pdb code 3p0n). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0n: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3p0nGo back to Zinc Binding Sites List in 3p0n
Zinc binding site 1 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3p0nGo back to Zinc Binding Sites List in 3p0n
Zinc binding site 2 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
E.Wahlberg,
T.Karlberg,
E.Kouznetsova,
N.Markova,
A.Macchiarulo,
A.G.Thorsell,
E.Pol,
A.Frostell,
T.Ekblad,
B.Kull,
G.M.Robertson,
R.Pellicciari,
H.Schuler,
J.Weigelt.
Family-Wide Chemical Profiling and Structural Analysis of Parp and Tankyrase Inhibitors Nat.Biotechnol. V. 30 283 2012.
Page generated: Wed Dec 16 04:42:01 2020
ISSN: ISSN 1087-0156 PubMed: 22343925 DOI: 10.1038/NBT.2121 |
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