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Atomistry » Zinc » PDB 3m1k-3m6o » 3m2n » |
Zinc in PDB 3m2n: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide, PDB code: 3m2n
was solved by
S.Grazulis,
E.Manakova,
D.Golovenko,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3m2n:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
(pdb code 3m2n). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide, PDB code: 3m2n: Zinc binding site 1 out of 1 in 3m2nGo back to Zinc Binding Sites List in 3m2n
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
Mono view Stereo pair view
Reference:
E.Capkauskaite,
A.Zubriene,
L.Baranauskiene,
G.Tamulaitiene,
E.Manakova,
V.Kairys,
S.Grazulis,
S.Tumkevicius,
D.Matulis.
Design of [(2-Pyrimidinylthio)Acetyl]Benzenesulfonamides As Inhibitors of Human Carbonic Anhydrases. Eur.J.Med.Chem. V. 51 259 2012.
Page generated: Wed Dec 16 04:33:46 2020
ISSN: ISSN 0223-5234 PubMed: 22440859 DOI: 10.1016/J.EJMECH.2012.02.050 |
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