Zinc in PDB 3lrn: Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna

The structure of Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna, PDB code: 3lrn was solved by P.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.50 / 2.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.490, 96.330, 103.400, 90.00, 90.00, 90.00
R / Rfree (%)	22.1 / 28.2

The binding sites of Zinc atom in the Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna (pdb code 3lrn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna, PDB code: 3lrn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:45.4 occ:1.00 SG A:CYS869 2.3 65.1 1.0 SG A:CYS864 2.4 42.9 1.0 SG A:CYS813 2.6 50.3 1.0 SG A:CYS810 2.7 39.7 1.0 CB A:CYS869 2.9 61.9 1.0 CB A:CYS864 3.2 50.1 1.0 CB A:CYS813 3.3 39.9 1.0 CB A:CYS810 3.3 41.8 1.0 N A:CYS813 3.6 42.7 1.0 CA A:CYS813 4.0 43.5 1.0 CB A:HIS871 4.4 44.4 1.0 CA A:CYS869 4.4 63.2 1.0 CB A:LYS812 4.5 48.4 1.0 CA A:CYS864 4.6 54.7 1.0 C A:LYS812 4.7 43.5 1.0 CA A:CYS810 4.8 29.7 1.0 N A:SER870 4.8 59.5 1.0 NE1 A:TRP873 4.8 19.8 1.0 N A:HIS871 4.8 50.4 1.0 C A:CYS869 4.8 60.1 1.0 CB A:ARG866 4.9 74.5 1.0 CZ2 A:TRP873 4.9 13.4 1.0 C A:CYS813 4.9 44.2 1.0 N A:LYS814 4.9 43.5 1.0 CA A:LYS812 5.0 44.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Rig-I Ctd Bound to A 14 Bp Gc 5' Ppp Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:44.2 occ:1.00 SG B:CYS869 2.2 41.7 1.0 SG B:CYS813 2.3 32.8 1.0 SG B:CYS864 2.3 37.7 1.0 SG B:CYS810 2.3 35.9 1.0 CB B:CYS869 3.1 48.0 1.0 CB B:CYS813 3.1 32.2 1.0 CB B:CYS810 3.1 29.5 1.0 CB B:CYS864 3.2 30.1 1.0 N B:CYS813 3.8 39.6 1.0 CA B:CYS813 4.0 38.4 1.0 CB B:HIS871 4.5 44.6 1.0 CA B:CYS869 4.5 52.2 1.0 CB B:ARG866 4.6 64.4 1.0 CA B:CYS810 4.6 25.2 1.0 CA B:CYS864 4.6 43.4 1.0 CZ2 B:TRP873 4.6 27.1 1.0 CB B:ALA815 4.7 43.4 1.0 C B:CYS813 4.7 39.5 1.0 N B:HIS871 4.8 45.7 1.0 NE1 B:TRP873 4.8 23.6 1.0 N B:LYS814 4.9 41.7 1.0 C B:LYS812 4.9 39.5 1.0 N B:SER870 4.9 44.6 1.0 C B:CYS869 5.0 49.8 1.0

C.Lu, H.Xu, C.T.Ranjith-Kumar, M.T.Brooks, T.Y.Hou, F.Hu, A.B.Herr, R.K.Strong, C.C.Kao, P.Li. The Structural Basis of 5' Triphosphate Double-Stranded Rna Recognition By Rig-I C-Terminal Domain. Structure V. 18 1032 2010.
ISSN: ISSN 0969-2126
PubMed: 20637642
DOI: 10.1016/J.STR.2010.05.007