Atomistry » Zinc » PDB 3jze-3kee » 3k7k
Atomistry »
  Zinc »
    PDB 3jze-3kee »
      3k7k »

Zinc in PDB 3k7k: Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions

Enzymatic activity of Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions

All present enzymatic activity of Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions:
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions, PDB code: 3k7k was solved by C.Temperini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 10.35 / 1.90
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.070, 41.410, 72.230, 90.00, 104.45, 90.00
R / Rfree (%) 19.4 / 24.8

Other elements in 3k7k:

The structure of Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions also contains other interesting chemical elements:

Mercury (Hg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions (pdb code 3k7k). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions, PDB code: 3k7k:

Zinc binding site 1 out of 1 in 3k7k

Go back to Zinc Binding Sites List in 3k7k
Zinc binding site 1 out of 1 in the Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn262

b:10.1
occ:1.00
 NE2 A:HIS94 2.0 8.1 1.0
ND1 A:HIS119 2.0 4.8 1.0
NE2 A:HIS96 2.0 7.2 1.0
SAD A:KCS301 2.1 53.6 1.0
CD2 A:HIS94 2.9 8.8 1.0
CE1 A:HIS119 2.9 4.1 1.0
CE1 A:HIS94 3.0 9.1 1.0
CE1 A:HIS96 3.0 7.3 1.0
CD2 A:HIS96 3.0 6.2 1.0
CG A:HIS119 3.1 5.2 1.0
CAB A:KCS301 3.2 55.8 1.0
CB A:HIS119 3.5 4.2 1.0
OG1 A:THR199 3.7 6.2 1.0
SAC A:KCS301 3.7 57.2 1.0
O A:HOH417 4.0 22.9 1.0
OE1 A:GLU106 4.0 6.5 1.0
CG A:HIS94 4.0 8.4 1.0
ND1 A:HIS94 4.1 8.5 1.0
NE2 A:HIS119 4.1 3.8 1.0
ND1 A:HIS96 4.1 6.2 1.0
CD2 A:HIS119 4.2 4.6 1.0
CG A:HIS96 4.2 6.4 1.0
SAA A:KCS301 4.5 56.7 1.0
O A:HOH400 4.8 26.4 1.0
CD A:GLU106 4.9 6.4 1.0
CA A:HIS119 5.0 4.7 1.0
O A:HOH402 5.0 24.5 1.0

Reference:

C.Temperini, A.Scozzafava, C.T.Supuran. Carbonic Anhydrase Inhibitors. X-Ray Crystal Studies of the Carbonic Anhydrase II-Trithiocarbonate Adduct-An Inhibitor Mimicking the Sulfonamide and Urea Binding to the Enzyme Bioorg.Med.Chem.Lett. V. 20 474 2010.
ISSN: ISSN 0960-894X
PubMed: 20005709
DOI: 10.1016/J.BMCL.2009.11.124
Page generated: Sat Oct 26 07:44:15 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy