Atomistry » Zinc » PDB 3jpy-3jyg » 3jt9
Atomistry »
  Zinc »
    PDB 3jpy-3jyg »
      3jt9 »

Zinc in PDB 3jt9: Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine

Enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine

All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine:
1.14.13.39;

Protein crystallography data

The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine, PDB code: 3jt9 was solved by H.Li, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.18 / 2.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.808, 110.861, 164.315, 90.00, 90.00, 90.00
R / Rfree (%) 18.4 / 22.7

Other elements in 3jt9:

The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine also contains other interesting chemical elements:

Iron (Fe) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine (pdb code 3jt9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine, PDB code: 3jt9:

Zinc binding site 1 out of 1 in 3jt9

Go back to Zinc Binding Sites List in 3jt9
Zinc binding site 1 out of 1 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Neuronal Nitric Oxide Synthase Heme Domain in the Ferrous State Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn900

b:46.0
occ:1.00
 SG A:CYS326 2.3 53.1 1.0
SG A:CYS331 2.3 48.0 1.0
SG B:CYS331 2.4 46.6 1.0
SG B:CYS326 2.4 51.6 1.0
CB B:CYS331 3.3 50.7 1.0
CB A:CYS331 3.3 50.9 1.0
CB A:CYS326 3.4 57.5 1.0
CB B:CYS326 3.5 57.8 1.0
CA B:CYS331 3.6 51.0 1.0
CA A:CYS331 3.7 52.6 1.0
N A:MET332 3.9 51.2 1.0
N B:MET332 4.0 48.6 1.0
N A:GLY333 4.1 47.7 1.0
N B:GLY333 4.1 46.6 1.0
C A:CYS331 4.2 51.5 1.0
C B:CYS331 4.2 50.1 1.0
CA B:GLY333 4.5 45.6 1.0
CA A:GLY333 4.5 46.0 1.0
CA A:CYS326 4.8 59.4 1.0
CA B:CYS326 4.8 59.2 1.0
N B:CYS331 4.8 54.1 1.0
O B:ILE330 4.9 56.4 1.0
C A:MET332 4.9 48.2 1.0
N A:CYS331 4.9 54.7 1.0

Reference:

J.D.Martell, H.Li, T.Doukov, P.Martasek, L.J.Roman, M.Soltis, T.L.Poulos, R.B.Silverman. Heme-Coordinating Inhibitors of Neuronal Nitric Oxide Synthase. Iron-Thioether Coordination Is Stabilized By Hydrophobic Contacts Without Increased Inhibitor Potency. J.Am.Chem.Soc. V. 132 798 2010.
ISSN: ISSN 0002-7863
PubMed: 20014790
DOI: 10.1021/JA908544F
Page generated: Wed Dec 16 04:28:44 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy