Zinc in PDB 3j80: Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex

The structure of Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex also contains other interesting chemical elements:

Magnesium

(Mg)

67 atoms

The binding sites of Zinc atom in the Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex (pdb code 3j80). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex, PDB code: 3j80:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ a:Zn500 b:0.0 occ:1.00 SG a:CYS74 1.9 0.8 1.0 SG a:CYS77 2.3 0.0 1.0 SG a:CYS23 2.7 0.2 1.0 CB a:CYS26 3.0 0.8 1.0 CB a:CYS77 3.0 0.9 1.0 CB a:CYS74 3.2 92.6 1.0 O a:CYS74 3.5 81.0 1.0 SG a:CYS26 3.6 0.4 1.0 N a:CYS26 3.6 0.6 1.0 CB a:CYS23 3.7 98.0 1.0 N a:CYS74 3.7 89.0 1.0 CA a:CYS74 3.9 86.8 1.0 CA a:CYS26 3.9 0.8 1.0 C a:CYS74 4.1 84.2 1.0 N a:CYS77 4.1 87.8 1.0 CA a:CYS77 4.2 91.4 1.0 OG a:SER76 4.4 97.4 1.0 CB a:ASN25 4.6 0.8 1.0 C a:ASN25 4.8 0.2 1.0 C a:TYR73 4.8 92.6 1.0 C a:CYS26 5.0 0.8 1.0 N a:ASN25 5.0 97.5 1.0

Zinc binding site 2 out of 3 in the Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ b:Zn101 b:0.7 occ:1.00 N b:CYS37 2.7 0.1 1.0 O b:ASN42 3.1 0.8 1.0 O b:VAL35 3.2 0.3 1.0 C b:LYS36 3.2 1.0 1.0 CB b:CYS37 3.2 0.2 1.0 SG b:CYS37 3.3 0.9 1.0 CA b:LYS36 3.3 0.1 1.0 CA b:CYS37 3.5 0.0 1.0 OG1 b:THR44 3.7 0.9 1.0 SG b:CYS56 3.8 0.1 1.0 C b:VAL35 3.8 0.9 1.0 CD2 b:LEU63 3.9 0.7 1.0 N b:LYS36 3.9 0.7 1.0 O b:LYS36 4.1 0.3 1.0 C b:ASN42 4.2 0.2 1.0 N b:THR44 4.6 0.6 1.0 CB b:LYS36 4.6 0.3 1.0 CA b:ILE43 4.7 0.2 1.0 C b:CYS37 4.8 0.4 1.0 CG b:LEU63 4.9 0.2 1.0 N b:ILE43 4.9 0.2 1.0 CD1 b:LEU63 4.9 0.5 1.0 C b:ILE43 5.0 0.7 1.0

Zinc binding site 3 out of 3 in the Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryoem Structure of 40S-EIF1-EIF1A Preinitiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn501 b:0.7 occ:1.00 SG f:CYS142 3.0 0.8 1.0 SG f:CYS121 3.0 0.5 1.0 CB f:CYS142 3.2 0.3 1.0 N f:CYS142 3.4 0.8 1.0 CB f:CYS139 3.6 0.8 1.0 CA f:CYS142 3.9 0.4 1.0 CB f:CYS124 4.1 0.4 1.0 CB f:CYS121 4.1 0.5 1.0 CD1 f:ILE128 4.2 0.7 1.0 CB f:LYS141 4.2 0.5 1.0 SG f:CYS124 4.2 0.0 1.0 C f:LYS141 4.3 0.9 1.0 N f:CYS124 4.4 0.8 1.0 SG f:CYS139 4.5 0.4 1.0 CA f:LYS141 4.6 0.5 1.0 CG2 f:ILE128 4.6 0.2 1.0 N f:LYS141 4.6 0.5 1.0 CB f:ASN123 4.6 0.1 1.0 CA f:CYS124 4.8 0.5 1.0 CA f:CYS139 4.9 0.0 1.0 C f:CYS139 4.9 0.4 1.0

T.Hussain, J.L.Llacer, I.S.Fernandez, A.Munoz, P.Martin-Marcos, C.G.Savva, J.R.Lorsch, A.G.Hinnebusch, V.Ramakrishnan. Structural Changes Enable Start Codon Recognition By the Eukaryotic Translation Initiation Complex Cell(Cambridge,Mass.) V. 159 597 2014.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2014.10.001