Zinc in PDB 3iow: Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg

The structure of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg, PDB code: 3iow was solved by M.W.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 3.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	101.097, 162.770, 139.660, 90.00, 98.85, 90.00
R / Rfree (%)	24.3 / 28.1

The structure of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg also contains other interesting chemical elements:

Calcium

(Ca)

10 atoms

The binding sites of Zinc atom in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg (pdb code 3iow). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg, PDB code: 3iow:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7;

Zinc binding site 1 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:1.0 occ:1.00 NZ A:LYS26 4.2 78.7 1.0

Zinc binding site 2 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:75.7 occ:1.00 O A:HIS39 2.0 78.1 1.0 ND1 A:HIS39 2.0 78.4 1.0 CE1 A:HIS39 2.8 78.5 1.0 CG A:HIS39 3.0 78.3 1.0 C A:HIS39 3.1 78.1 1.0 CB A:HIS39 3.5 78.1 1.0 NE2 A:HIS39 3.9 78.8 1.0 CA A:HIS39 3.9 78.1 1.0 CD2 A:HIS39 4.0 78.5 1.0 N A:PRO40 4.2 78.1 1.0 CA A:PRO40 4.4 78.1 1.0 C A:PRO40 4.5 78.2 1.0 N A:HIS39 4.6 78.0 1.0 O A:PRO40 4.7 78.2 1.0 CA A:GLY13 4.8 78.1 1.0 N A:ASP41 4.8 78.2 1.0

Zinc binding site 3 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:0.7 occ:1.00 CE1 A:HIS203 2.7 78.2 1.0 NE2 A:HIS203 3.3 78.1 1.0 ND1 A:HIS203 3.9 78.2 1.0 CB A:ASN201 4.1 78.2 1.0 CG A:ASN201 4.2 78.2 1.0 OD1 A:ASN201 4.3 78.2 1.0 CB A:PRO133 4.3 78.1 1.0 CD2 A:HIS203 4.7 78.2 1.0 ND2 A:ASN201 4.9 78.2 1.0 CG A:HIS203 4.9 78.1 1.0

Zinc binding site 4 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:0.6 occ:0.70 ND1 B:HIS39 2.7 78.9 1.0 CE1 B:HIS39 3.0 78.9 1.0 O B:HIS39 3.3 78.2 1.0 CG B:HIS39 4.0 78.6 1.0 NE2 B:HIS39 4.2 79.0 1.0 C B:HIS39 4.5 78.2 1.0 CB B:HIS39 4.7 78.3 1.0 CD2 B:HIS39 4.7 78.9 1.0

Zinc binding site 5 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:92.7 occ:1.00 CE1 B:HIS203 2.6 78.1 1.0 NE2 B:HIS203 3.2 78.1 1.0 ND1 B:HIS203 3.8 78.2 1.0 CE B:LYS137 3.8 78.6 1.0 CB B:ASN201 4.0 78.2 1.0 CG B:ASN201 4.1 78.1 1.0 OD1 B:ASN201 4.3 78.2 1.0 CB B:PRO133 4.4 78.1 1.0 NZ B:LYS137 4.5 78.6 1.0 CD2 B:HIS203 4.6 78.2 1.0 ND2 B:ASN201 4.6 78.1 1.0 CG B:HIS203 4.8 78.1 1.0 CD B:LYS137 5.0 78.5 1.0

Zinc binding site 6 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn501 b:73.5 occ:1.00 O C:HIS39 2.1 78.1 1.0 ND1 C:HIS39 2.2 78.1 1.0 CE1 C:HIS39 2.8 78.2 1.0 CG C:HIS39 3.2 78.1 1.0 C C:HIS39 3.3 78.1 1.0 CB C:HIS39 3.7 78.1 1.0 NE2 C:HIS39 3.9 78.3 1.0 CA C:HIS39 4.0 78.1 1.0 CD2 C:HIS39 4.1 78.1 1.0 N C:PRO40 4.3 78.1 1.0 CA C:PRO40 4.4 78.0 1.0 C C:PRO40 4.5 78.1 1.0 N C:HIS39 4.7 78.1 1.0 O C:PRO40 4.8 78.1 1.0 N C:ASP41 4.9 78.1 1.0 CA C:GLY13 4.9 78.1 1.0

Zinc binding site 7 out of 7 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99-Hg within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn502 b:96.7 occ:1.00 CE1 C:HIS203 2.7 78.3 1.0 NE2 C:HIS203 3.3 78.3 1.0 ND1 C:HIS203 3.8 78.3 1.0 CB C:ASN201 4.1 78.2 1.0 CG C:ASN201 4.2 78.1 1.0 OD1 C:ASN201 4.3 78.1 1.0 CB C:PRO133 4.3 78.2 1.0 CD2 C:HIS203 4.6 78.2 1.0 ND2 C:ASN201 4.8 78.2 1.0 CG C:HIS203 4.9 78.2 1.0 O C:PRO133 5.0 78.2 1.0

M.W.Kim, Y.Chelliah, S.W.Kim, Z.Otwinowski, I.Bezprozvanny. Secondary Structure of Huntingtin Amino-Terminal Region. Structure V. 17 1205 2009.
ISSN: ISSN 0969-2126
PubMed: 19748341
DOI: 10.1016/J.STR.2009.08.002