Zinc in PDB 3iov: Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99

The structure of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99, PDB code: 3iov was solved by M.W.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.00 / 3.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	163.820, 101.190, 134.820, 90.00, 99.23, 90.00
R / Rfree (%)	26.4 / 28

The structure of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 also contains other interesting chemical elements:

Calcium

(Ca)

7 atoms

The binding sites of Zinc atom in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 (pdb code 3iov). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99, PDB code: 3iov:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:76.3 occ:1.00 ND1 A:HIS39 2.5 80.0 1.0 O A:HIS39 2.8 77.1 1.0 CE1 A:HIS39 3.3 80.9 1.0 CG A:HIS39 3.6 79.0 1.0 C A:HIS39 3.9 77.2 1.0 CB A:HIS39 4.0 77.4 1.0 CA A:GLY13 4.2 78.7 1.0 NE2 A:HIS39 4.5 80.9 1.0 O A:PRO40 4.6 79.2 1.0 CA A:HIS39 4.6 77.0 1.0 N A:GLY13 4.7 77.3 1.0 CD2 A:HIS39 4.7 80.3 1.0 C A:PRO40 4.8 79.1 1.0 OD1 A:ASP41 4.8 85.1 1.0 N A:PRO40 5.0 77.5 1.0

Zinc binding site 2 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:0.6 occ:1.00 CE1 A:HIS203 2.7 86.6 1.0 OD1 A:ASN201 3.0 90.1 1.0 ND2 A:ASN201 3.1 90.4 1.0 NE2 A:HIS203 3.1 86.8 1.0 CG A:ASN201 3.2 90.7 1.0 ND1 A:HIS203 3.9 86.5 1.0 CB A:ASN201 4.3 90.4 1.0 CD2 A:HIS203 4.3 86.6 1.0 O A:ASN201 4.5 90.6 1.0 CG A:HIS203 4.7 86.5 1.0

Zinc binding site 3 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:0.4 occ:1.00 ND2 B:ASN201 2.8 90.7 1.0 NE2 B:HIS203 3.3 87.0 1.0 CE1 B:HIS203 3.5 86.9 1.0 CG B:ASN201 3.9 91.0 1.0 CB B:ASN201 4.3 91.5 1.0 CD2 B:HIS203 4.5 87.0 1.0 O B:ASN201 4.6 91.7 1.0 ND1 B:HIS203 4.7 87.0 1.0 OD1 B:ASN201 5.0 90.5 1.0

Zinc binding site 4 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:99.0 occ:1.00 OE1 B:GLU291 2.8 89.5 1.0 OE2 B:GLU291 3.3 89.4 1.0 CD B:GLU291 3.4 88.4 1.0 OE1 B:GLU310 4.2 90.9 1.0 CG B:GLU291 4.9 86.0 1.0 OE2 B:GLU288 5.0 92.8 1.0

Zinc binding site 5 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn503 b:65.4 occ:1.00 O B:HIS39 2.3 81.7 1.0 CD2 B:HIS39 2.4 81.1 1.0 NE2 B:HIS39 2.9 81.2 1.0 CG B:HIS39 3.0 81.2 1.0 C B:HIS39 3.5 81.8 1.0 CB B:HIS39 3.7 81.3 1.0 CE1 B:HIS39 3.7 81.2 1.0 ND1 B:HIS39 3.8 81.2 1.0 CA B:HIS39 4.2 81.3 1.0 CA B:GLY13 4.2 80.5 1.0 N B:PRO40 4.6 82.3 1.0 O B:PRO40 4.7 83.8 1.0 CA B:PRO40 4.8 83.0 1.0 N B:GLY13 4.8 79.8 1.0 C B:PRO40 4.8 83.6 1.0

Zinc binding site 6 out of 6 in the Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Huntingtin Amino-Terminal Region with 17 Gln Residues - Crystal C99 within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn501 b:0.1 occ:1.00 CE1 C:HIS203 2.7 86.4 1.0 NE2 C:HIS203 3.1 86.5 1.0 ND2 C:ASN201 3.9 90.2 1.0 ND1 C:HIS203 3.9 86.3 1.0 CG C:ASN201 4.0 90.0 1.0 CB C:ASN201 4.1 89.5 1.0 CD2 C:HIS203 4.4 86.3 1.0 OD1 C:ASN201 4.6 89.9 1.0 CG C:HIS203 4.8 86.1 1.0 CB C:PRO133 4.9 81.5 1.0

M.W.Kim, Y.Chelliah, S.W.Kim, Z.Otwinowski, I.Bezprozvanny. Secondary Structure of Huntingtin Amino-Terminal Region. Structure V. 17 1205 2009.
ISSN: ISSN 0969-2126
PubMed: 19748341
DOI: 10.1016/J.STR.2009.08.002