Zinc in PDB 3ifu: The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1

The structure of The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1, PDB code: 3ifu was solved by Y.Sun, F.Xue, Y.Guo, M.Ma, Z.Lou, Z.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.42
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	51.000, 51.000, 154.600, 90.00, 90.00, 90.00
R / Rfree (%)	22.3 / 25.7

The binding sites of Zinc atom in the The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1 (pdb code 3ifu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1, PDB code: 3ifu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn181 b:64.8 occ:1.00 OXT A:MET180 2.1 51.6 1.0 ND1 A:HIS146 2.2 41.2 1.0 SG A:CYS70 2.4 54.3 1.0 SG A:CYS76 2.5 40.7 1.0 C A:MET180 2.8 51.1 1.0 CB A:CYS70 3.0 53.1 1.0 O A:MET180 3.1 51.1 1.0 CE1 A:HIS146 3.1 38.7 1.0 CG A:HIS146 3.2 43.5 1.0 CB A:CYS76 3.3 41.6 1.0 CB A:HIS146 3.5 41.3 1.0 CA A:CYS70 3.7 53.3 1.0 CA A:HIS146 4.1 42.0 1.0 O A:LEU145 4.2 47.0 1.0 CA A:MET180 4.2 51.1 1.0 N A:CYS76 4.2 44.5 1.0 N A:MET180 4.2 50.2 1.0 NE2 A:HIS146 4.3 41.8 1.0 CD2 A:HIS146 4.3 42.6 1.0 CA A:CYS76 4.4 43.5 1.0 C A:CYS70 4.6 52.4 1.0 O A:GLU69 4.7 57.6 1.0 N A:CYS70 4.8 55.9 1.0 C A:LEU145 4.9 46.2 1.0 N A:HIS146 4.9 44.0 1.0 N A:SER71 4.9 50.6 1.0 N A:VAL147 5.0 39.9 1.0

Zinc binding site 2 out of 2 in the The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (Prrsv) Leader Protease NSP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn182 b:68.7 occ:1.00 SG A:CYS25 2.4 48.0 1.0 SG A:CYS28 2.4 51.6 1.0 SG A:CYS10 2.5 59.5 1.0 SG A:CYS8 2.5 58.1 1.0 CB A:CYS25 3.1 45.1 1.0 CB A:CYS10 3.2 61.2 1.0 CB A:CYS28 3.5 50.9 1.0 CB A:CYS8 3.6 63.6 1.0 N A:CYS28 3.7 52.4 1.0 N A:CYS10 4.0 61.6 1.0 CA A:CYS28 4.2 51.1 1.0 CA A:CYS10 4.2 60.8 1.0 CB A:ARG27 4.3 56.4 1.0 CA A:CYS8 4.4 64.6 1.0 NH1 A:ARG32 4.4 58.7 1.0 N A:THR9 4.5 63.9 1.0 CA A:CYS25 4.6 46.1 1.0 C A:ARG27 4.7 53.0 1.0 C A:CYS8 4.7 64.5 1.0 CA A:ARG27 4.8 54.0 1.0 N A:ARG27 4.9 53.6 1.0 C A:CYS28 4.9 50.6 1.0

Y.Sun, F.Xue, Y.Guo, M.Ma, N.Hao, X.C.Zhang, Z.Lou, X.Li, Z.Rao. Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus Leader Protease NSP1ALPHA J.Virol. V. 83 10931 2009.
ISSN: ISSN 0022-538X
PubMed: 19706710
DOI: 10.1128/JVI.02579-08