Zinc in PDB 4dxx: Tgt K52M Mutant Crystallized at pH 8.5

All present enzymatic activity of Tgt K52M Mutant Crystallized at pH 8.5:
2.4.2.29;

The structure of Tgt K52M Mutant Crystallized at pH 8.5, PDB code: 4dxx was solved by S.Jakobi, T.Ritschel, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.85 / 1.66
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	91.220, 64.865, 70.082, 90.00, 95.99, 90.00
R / Rfree (%)	16.6 / 19.9

The binding sites of Zinc atom in the Tgt K52M Mutant Crystallized at pH 8.5 (pdb code 4dxx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tgt K52M Mutant Crystallized at pH 8.5, PDB code: 4dxx:

Zinc binding site 1 out of 1 in the Tgt K52M Mutant Crystallized at pH 8.5


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Tgt K52M Mutant Crystallized at pH 8.5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:9.7 occ:1.00 ND1 A:HIS349 2.1 8.6 1.0 SG A:CYS323 2.3 9.4 1.0 SG A:CYS320 2.3 9.4 1.0 SG A:CYS318 2.3 10.6 1.0 CE1 A:HIS349 2.9 9.5 1.0 CB A:CYS318 3.2 10.6 1.0 CG A:HIS349 3.2 6.1 1.0 CB A:CYS323 3.3 8.4 1.0 CB A:CYS320 3.4 6.6 1.0 CB A:HIS349 3.7 8.1 1.0 N A:CYS323 3.9 8.6 1.0 NE2 A:HIS349 4.1 9.0 1.0 CA A:HIS349 4.1 6.6 1.0 N A:CYS320 4.1 9.2 1.0 CA A:CYS323 4.2 9.3 1.0 CA A:CYS320 4.2 8.2 1.0 CD2 A:HIS349 4.3 9.0 1.0 O A:HIS349 4.5 9.3 1.0 CA A:CYS318 4.6 10.7 1.0 O A:CYS320 4.7 10.1 1.0 C A:CYS320 4.7 10.3 1.0 C A:CYS318 4.7 11.1 1.0 C A:HIS349 4.8 9.5 1.0 O A:CYS318 4.8 13.3 1.0 CB A:VAL322 4.9 7.3 1.0 C A:VAL322 4.9 11.0 1.0

S.Jakobi, T.X.Nguyen, F.Debaene, A.Metz, S.Sanglier-Cianferani, K.Reuter, G.Klebe. Hot-Spot Analysis to Dissect the Functional Protein-Protein Interface of A Trna-Modifying Enzyme. Proteins V. 82 2713 2014.
ISSN: ISSN 0887-3585
PubMed: 24975703
DOI: 10.1002/PROT.24637