Zinc in PDB 3hqh: Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1

The structure of Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1, PDB code: 3hqh was solved by M.Zhuang, B.A.Schulman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	44.700, 44.700, 268.000, 90.00, 90.00, 120.00
R / Rfree (%)	23.8 / 27.6

The binding sites of Zinc atom in the Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1 (pdb code 3hqh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1, PDB code: 3hqh:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:73.6 occ:0.50 OE2 A:GLU47 2.5 55.2 1.0 SG A:CYS44 2.7 61.5 1.0 CG A:GLU47 3.2 46.6 1.0 CD A:GLU47 3.2 50.1 1.0 OE2 A:GLU46 3.2 63.9 1.0 ZN A:ZN202 3.5 78.5 1.0 CB A:CYS44 3.7 49.7 1.0 CG A:GLU46 3.8 56.1 1.0 CD A:GLU46 3.9 60.0 1.0 OE1 A:GLU47 4.4 49.9 1.0 CB A:GLU47 4.4 45.4 1.0

Zinc binding site 2 out of 3 in the Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:78.5 occ:1.00 SG A:CYS44 2.5 61.5 1.0 CB A:CYS44 3.1 49.7 1.0 O A:HOH327 3.3 55.2 1.0 ZN A:ZN201 3.5 73.6 0.5 OE2 A:GLU46 3.6 63.9 1.0 CA A:CYS44 3.8 48.7 1.0 CD A:GLU46 4.2 60.0 1.0 CG A:GLU46 4.5 56.1 1.0 C A:CYS44 4.6 46.8 1.0 N A:ARG45 4.7 46.6 1.0 N A:CYS44 4.9 48.8 1.0 OE1 A:GLU46 5.0 61.0 1.0

Zinc binding site 3 out of 3 in the Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmathx- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:60.6 occ:1.00 OE1 A:GLU113 2.3 55.4 1.0 OE2 A:GLU160 2.5 41.4 1.0 OE2 A:GLU113 2.8 55.0 1.0 CD A:GLU113 2.9 54.6 1.0 CD A:GLU160 3.3 40.2 1.0 OE1 A:GLU160 3.5 40.0 1.0 NZ A:LYS103 3.5 48.4 1.0 CE2 A:PHE158 4.2 30.1 1.0 CG A:GLU113 4.3 53.2 1.0 CE A:LYS103 4.4 42.1 1.0 CD2 A:PHE158 4.5 32.4 1.0 O A:HOH320 4.5 29.9 1.0 CG A:GLU160 4.6 39.0 1.0

M.Zhuang, M.F.Calabrese, J.Liu, M.B.Waddell, A.Nourse, M.Hammel, D.J.Miller, H.Walden, D.M.Duda, S.N.Seyedin, T.Hoggard, J.W.Harper, K.P.White, B.A.Schulman. Structures of Spop-Substrate Complexes: Insights Into Molecular Architectures of Btb-CUL3 Ubiquitin Ligases. Mol.Cell V. 36 39 2009.
ISSN: ISSN 1097-2765
PubMed: 19818708
DOI: 10.1016/J.MOLCEL.2009.09.022