Zinc in PDB 3gpx: Sequence-Matched Mutm Interrogation Complex 4 (IC4)

All present enzymatic activity of Sequence-Matched Mutm Interrogation Complex 4 (IC4):
4.2.99.18;

The structure of Sequence-Matched Mutm Interrogation Complex 4 (IC4), PDB code: 3gpx was solved by M.C.Spong, Y.Qi, G.L.Verdine, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.49 / 1.78
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.188, 93.541, 104.650, 90.00, 90.00, 90.00
R / Rfree (%)	18.9 / 21.8

The binding sites of Zinc atom in the Sequence-Matched Mutm Interrogation Complex 4 (IC4) (pdb code 3gpx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sequence-Matched Mutm Interrogation Complex 4 (IC4), PDB code: 3gpx:

Zinc binding site 1 out of 1 in the Sequence-Matched Mutm Interrogation Complex 4 (IC4)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sequence-Matched Mutm Interrogation Complex 4 (IC4) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn300 b:19.5 occ:1.00 SG A:CYS272 2.3 27.0 1.0 SG A:CYS249 2.3 18.7 1.0 SG A:CYS269 2.3 19.7 1.0 SG A:CYS252 2.3 17.8 1.0 CB A:CYS249 3.1 19.7 1.0 CB A:CYS269 3.3 17.7 1.0 CB A:CYS272 3.4 22.1 1.0 CB A:CYS252 3.4 20.5 1.0 N A:CYS252 3.9 20.3 1.0 N A:CYS272 3.9 22.0 1.0 CE1 A:PHE182 4.2 19.6 1.0 CA A:CYS252 4.2 19.7 1.0 CA A:CYS272 4.2 22.1 1.0 O A:HOH311 4.4 36.9 1.0 CB A:ARG251 4.5 21.3 0.5 CB A:ARG251 4.6 21.4 0.5 CA A:CYS249 4.6 20.7 1.0 CZ A:PHE182 4.6 20.9 1.0 CB A:ARG271 4.6 21.8 1.0 C A:ARG251 4.7 20.9 0.5 CB A:THR254 4.7 20.2 1.0 CA A:CYS269 4.7 18.8 1.0 C A:ARG251 4.8 20.8 0.5 C A:CYS252 4.8 19.8 1.0 N A:GLY253 4.9 19.5 1.0 C A:ARG271 4.9 22.6 1.0 N A:THR254 5.0 19.5 1.0 N A:ARG251 5.0 20.8 0.5 N A:ARG251 5.0 20.8 0.5 CA A:ARG251 5.0 21.1 0.5 OG1 A:THR254 5.0 21.3 1.0

Y.Qi, M.C.Spong, K.Nam, A.Banerjee, S.Jiralerspong, M.Karplus, G.L.Verdine. Encounter and Extrusion of An Intrahelical Lesion By A Dna Repair Enzyme. Nature V. 462 762 2009.
ISSN: ISSN 0028-0836
PubMed: 20010681
DOI: 10.1038/NATURE08561