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Atomistry » Zinc » PDB 3e2d-3eb5 » 3e37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3e2d-3eb5 » 3e37 » |
Zinc in PDB 3e37: Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5Enzymatic activity of Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5
All present enzymatic activity of Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5:
2.5.1.58; 2.5.1.59; Protein crystallography data
The structure of Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5, PDB code: 3e37
was solved by
M.A.Hast,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5
(pdb code 3e37). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5, PDB code: 3e37: Zinc binding site 1 out of 1 in 3e37Go back to Zinc Binding Sites List in 3e37
Zinc binding site 1 out
of 1 in the Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5
Mono view Stereo pair view
Reference:
M.A.Hast,
S.Fletcher,
C.G.Cummings,
E.E.Pusateri,
M.A.Blaskovich,
K.Rivas,
M.H.Gelb,
W.C.Van Voorhis,
S.M.Sebti,
A.D.Hamilton,
L.S.Beese.
Structural Basis For Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase. Chem.Biol. V. 16 181 2009.
Page generated: Thu Oct 24 12:35:31 2024
ISSN: ISSN 1074-5521 PubMed: 19246009 DOI: 10.1016/J.CHEMBIOL.2009.01.014 |
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