Atomistry » Zinc » PDB 3dgl-3dsu » 3ds9
Atomistry »
  Zinc »
    PDB 3dgl-3dsu »
      3ds9 »

Zinc in PDB 3ds9: A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate

Enzymatic activity of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate

All present enzymatic activity of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate:
3.4.24.69;

Protein crystallography data

The structure of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate, PDB code: 3ds9 was solved by J.E.Zuniga, T.Fenn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.01 / 1.76
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 58.799, 189.205, 42.303, 90.00, 90.00, 90.00
R / Rfree (%) 21.3 / 24.8

Other elements in 3ds9:

The structure of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate also contains other interesting chemical elements:

Nickel (Ni) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate (pdb code 3ds9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate, PDB code: 3ds9:

Zinc binding site 1 out of 1 in 3ds9

Go back to Zinc Binding Sites List in 3ds9
Zinc binding site 1 out of 1 in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn500

b:18.2
occ:1.00
 NE2 A:HIS227 2.1 17.5 1.0
NE2 A:HIS223 2.1 14.6 1.0
OE1 A:GLU262 2.2 17.3 1.0
OE2 A:GLU262 2.2 13.9 1.0
O B:01W197 2.2 15.9 1.0
N B:01W197 2.3 17.5 1.0
CD A:GLU262 2.5 17.4 1.0
C B:01W197 3.0 14.8 1.0
CD2 A:HIS227 3.0 17.1 1.0
CD2 A:HIS223 3.1 17.8 1.0
CA B:01W197 3.1 13.6 1.0
CE1 A:HIS227 3.1 12.8 1.0
CE1 A:HIS223 3.2 15.4 1.0
CB B:01W197 3.7 19.8 1.0
CG A:GLU262 4.0 20.2 1.0
OH A:TYR366 4.0 15.7 1.0
CG A:HIS227 4.2 12.5 1.0
ND1 A:HIS227 4.2 14.7 1.0
CG A:HIS223 4.2 15.3 1.0
N B:ARG198 4.3 17.1 1.0
ND1 A:HIS223 4.3 13.8 1.0
OE2 A:GLU224 4.3 16.0 1.0
CE1 A:TYR366 4.4 8.1 1.0
O A:HOH630 4.4 24.7 1.0
O A:HOH811 4.5 18.0 1.0
CZ A:TYR366 4.6 13.9 1.0
CB A:GLU262 4.8 19.1 1.0
CA B:ARG198 4.9 13.8 1.0
C1 B:01W197 5.0 25.2 1.0
C7 B:01W197 5.0 19.1 1.0
OE1 A:GLU224 5.0 17.8 1.0

Reference:

J.E.Zuniga, J.J.Schmidt, T.Fenn, J.C.Burnett, D.Arac, R.Gussio, R.G.Stafford, S.S.Badie, S.Bavari, A.T.Brunger. A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate Structure V. 16 1588 2008.
ISSN: ISSN 0969-2126
PubMed: 18940613
DOI: 10.1016/J.STR.2008.07.011
Page generated: Thu Oct 24 12:19:06 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy