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Atomistry » Zinc » PDB 3dgl-3dsu » 3dqt » |
Zinc in PDB 3dqt: Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-DiamineEnzymatic activity of Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine
All present enzymatic activity of Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine:
1.14.13.39; Protein crystallography data
The structure of Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine, PDB code: 3dqt
was solved by
J.Igarashi,
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3dqt:
The structure of Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine
(pdb code 3dqt). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine, PDB code: 3dqt: Zinc binding site 1 out of 1 in 3dqtGo back to Zinc Binding Sites List in 3dqt
Zinc binding site 1 out
of 1 in the Structure of Endothelial Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Trans-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Chlorobenzyl)Ethane-1,2-Diamine
Mono view Stereo pair view
Reference:
J.Igarashi,
H.Li,
J.Jamal,
H.Ji,
J.Fang,
G.R.Lawton,
R.B.Silverman,
T.L.Poulos.
Crystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors. J.Med.Chem. V. 52 2060 2009.
Page generated: Thu Oct 24 12:18:45 2024
ISSN: ISSN 0022-2623 PubMed: 19296678 DOI: 10.1021/JM900007A |
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