Zinc in PDB 3cki: Crystal Structure of the Tace-N-Timp-3 Complex

All present enzymatic activity of Crystal Structure of the Tace-N-Timp-3 Complex:
3.4.24.86;

The structure of Crystal Structure of the Tace-N-Timp-3 Complex, PDB code: 3cki was solved by M.Wisniewska, P.Goettig, K.Maskos, E.Belouski, D.Winters, R.Hecht, R.Black, W.Bode, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.59 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	70.447, 70.447, 156.728, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 28.4

The structure of Crystal Structure of the Tace-N-Timp-3 Complex also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the Tace-N-Timp-3 Complex (pdb code 3cki). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Tace-N-Timp-3 Complex, PDB code: 3cki:

Zinc binding site 1 out of 1 in the Crystal Structure of the Tace-N-Timp-3 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Tace-N-Timp-3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:38.2 occ:1.00 N B:CYS1 1.9 27.9 1.0 NE2 A:HIS405 2.2 15.1 1.0 NE2 A:HIS415 2.2 32.5 1.0 NE2 A:HIS409 2.2 25.9 1.0 O B:CYS1 2.4 26.0 1.0 CA B:CYS1 2.9 28.9 1.0 C B:CYS1 2.9 27.1 1.0 CD2 A:HIS415 3.0 27.6 1.0 CD2 A:HIS405 3.0 19.4 1.0 CE1 A:HIS409 3.2 28.2 1.0 CD2 A:HIS409 3.2 19.3 1.0 CE1 A:HIS405 3.3 17.5 1.0 CE1 A:HIS415 3.3 25.9 1.0 CB B:CYS1 3.6 33.5 1.0 N B:THR2 4.1 26.8 1.0 CG A:HIS415 4.2 30.1 1.0 CG A:HIS405 4.2 20.1 1.0 OE1 A:GLU406 4.3 33.4 1.0 ND1 A:HIS409 4.3 25.1 1.0 ND1 A:HIS405 4.3 16.9 1.0 ND1 A:HIS415 4.3 26.9 1.0 CG A:HIS409 4.3 23.5 1.0 OE2 A:GLU406 4.5 30.1 1.0 CA B:SER66 4.5 34.6 1.0 O B:SER66 4.5 29.2 1.0 CG2 B:THR2 4.6 30.7 1.0 CD A:GLU406 4.8 27.6 1.0 CA B:THR2 4.8 27.2 1.0 O B:GLU65 4.9 41.9 1.0 CE A:MET435 4.9 22.0 1.0 C B:SER66 5.0 33.4 1.0

M.Wisniewska, P.Goettig, K.Maskos, E.Belouski, D.Winters, R.Hecht, R.Black, W.Bode. Structural Determinants of the Adam Inhibition By Timp-3: Crystal Structure of the Tace-N-Timp-3 Complex. J.Mol.Biol. V. 381 1307 2008.
ISSN: ISSN 0022-2836
PubMed: 18638486
DOI: 10.1016/J.JMB.2008.06.088