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Zinc in PDB 3b4f: Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies
Enzymatic activity of Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies
All present enzymatic activity of Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies, PDB code: 3b4f
was solved by
O.Guzel,
C.Temperini,
A.Innocenti,
A.Scozzafava,
A.Salman,
C.T.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 1.89 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.000, 41.350, 72.340, 90.00, 104.35, 90.00 |
| R / Rfree (%) | 19.6 / 23.9 |
Other elements in 3b4f:
The structure of Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies also contains other interesting chemical elements:
| Mercury | (Hg) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies
(pdb code 3b4f). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies, PDB code: 3b4f:
In total only one binding site of Zinc was determined in the Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies, PDB code: 3b4f:
Zinc binding site 1 out of 1 in 3b4f
Go back to
Zinc Binding Sites List in 3b4f
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3- Phenyl-1H-Indole-5-Sulfonamide with Twelve Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies within 5.0Å range:
|
Reference:
O.Guzel,
C.Temperini,
A.Innocenti,
A.Scozzafava,
A.Salman,
C.T.Supuran.
Carbonic Anhydrase Inhibitors. Interaction of 2-(Hydrazinocarbonyl)-3-Phenyl-1H-Indole-5-Sulfonamide with 12 Mammalian Isoforms: Kinetic and X-Ray Crystallographic Studies. Bioorg.Med.Chem.Lett. V. 18 152 2008.
ISSN: ISSN 0960-894X
PubMed: 18024029
DOI: 10.1016/J.BMCL.2007.10.110
Page generated: Thu Oct 24 11:25:38 2024
ISSN: ISSN 0960-894X
PubMed: 18024029
DOI: 10.1016/J.BMCL.2007.10.110
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