Zinc in PDB 2zze: Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form

All present enzymatic activity of Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form:
6.1.1.7;

The structure of Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form, PDB code: 2zze was solved by M.Sokabe, T.Ose, K.Tokunaga, A.Nakamura, O.Nureki, M.Yao, I.Tanaka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.58 / 2.16
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	89.063, 130.151, 94.855, 90.00, 117.46, 90.00
R / Rfree (%)	18.9 / 22.7

The binding sites of Zinc atom in the Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form (pdb code 2zze). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form, PDB code: 2zze:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn753 b:16.4 occ:1.00 SG A:CYS23 2.2 13.2 1.0 SG A:CYS42 2.3 16.9 1.0 SG A:CYS37 2.3 10.9 1.0 SG A:CYS20 2.4 10.7 1.0 CB A:CYS42 3.2 19.3 1.0 CB A:CYS20 3.2 11.1 1.0 CB A:CYS23 3.2 12.2 1.0 CB A:CYS37 3.3 12.1 1.0 O A:HOH800 3.6 19.5 1.0 N A:CYS23 3.7 12.3 1.0 N A:CYS37 3.8 12.0 1.0 CA A:CYS23 4.1 12.3 1.0 CA A:CYS37 4.2 12.0 1.0 NZ A:LYS188 4.3 17.5 1.0 O A:ASP39 4.6 15.8 1.0 CE A:LYS188 4.6 14.6 1.0 CA A:CYS42 4.7 19.2 1.0 CA A:CYS20 4.7 11.5 1.0 C A:CYS23 4.8 12.1 1.0 CB A:VAL22 4.8 12.0 1.0 C A:VAL22 4.8 12.2 1.0 C A:THR36 5.0 11.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Alanyl-Trna Synthetase Without Oligomerization Domain in Lysine-Methylated Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn753 b:17.2 occ:1.00 SG B:CYS42 2.2 14.8 1.0 SG B:CYS37 2.2 14.6 1.0 SG B:CYS23 2.3 14.9 1.0 SG B:CYS20 2.4 11.4 1.0 CB B:CYS42 3.1 18.1 1.0 CB B:CYS20 3.2 11.2 1.0 CB B:CYS23 3.2 13.8 1.0 CB B:CYS37 3.3 14.6 1.0 O B:HOH1022 3.6 19.0 1.0 N B:CYS23 3.8 13.6 1.0 N B:CYS37 3.9 14.1 1.0 NZ B:LYS188 4.1 17.7 1.0 CA B:CYS23 4.1 14.2 1.0 CA B:CYS37 4.2 14.5 1.0 CA B:CYS42 4.6 18.2 1.0 O B:ASP39 4.6 17.5 1.0 CA B:CYS20 4.7 11.8 1.0 CE B:LYS188 4.7 16.0 1.0 CB B:VAL22 4.7 13.0 1.0 C B:CYS23 4.9 14.2 1.0 C B:VAL22 4.9 13.4 1.0

M.Sokabe, T.Ose, A.Nakamura, K.Tokunaga, O.Nureki, M.Yao, I.Tanaka. The Structure of Alanyl-Trna Synthetase with Editing Domain. Proc.Natl.Acad.Sci.Usa V. 106 11028 2009.
ISSN: ISSN 0027-8424
PubMed: 19549823
DOI: 10.1073/PNAS.0904645106