Zinc in PDB 2zkw: Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21

All present enzymatic activity of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21:
1.15.1.1;

The structure of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21, PDB code: 2zkw was solved by S.Yoshikawa, M.Kukimoto-Niino, K.Ito, L.Chen, Z.Q.Fu, J.Chrzas, B.C.Wang, M.Shirouzu, M.Urushitani, R.Takahashi, S.Yokoyama, Riken Structuralgenomics/Proteomics Initiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.46 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	48.616, 46.233, 52.818, 90.00, 94.42, 90.00
R / Rfree (%)	19.3 / 25.2

The structure of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21 also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21 (pdb code 2zkw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21, PDB code: 2zkw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:27.6 occ:1.00 ND1 A:HIS80 1.9 26.4 1.0 ND1 A:HIS71 2.0 26.2 1.0 OD1 A:ASP83 2.0 25.7 1.0 ND1 A:HIS63 2.1 24.1 1.0 CG A:ASP83 2.7 21.5 1.0 OD2 A:ASP83 2.7 25.7 1.0 CE1 A:HIS80 2.8 26.9 1.0 CE1 A:HIS71 2.8 32.7 1.0 CG A:HIS80 3.0 29.4 1.0 CG A:HIS71 3.1 26.1 1.0 CG A:HIS63 3.1 27.7 1.0 CE1 A:HIS63 3.1 30.1 1.0 CB A:HIS63 3.4 28.7 1.0 CB A:HIS80 3.4 25.0 1.0 CB A:HIS71 3.5 24.7 1.0 CA A:HIS71 3.9 25.2 1.0 NE2 A:HIS80 3.9 27.8 1.0 NE2 A:HIS71 4.0 25.0 1.0 CD2 A:HIS80 4.0 22.5 1.0 CD2 A:HIS71 4.1 34.8 1.0 CB A:ASP83 4.1 28.0 1.0 O A:LYS136 4.2 42.2 1.0 NE2 A:HIS63 4.2 23.5 1.0 CD2 A:HIS63 4.2 29.0 1.0 N A:HIS80 4.6 25.1 1.0 CA A:HIS80 4.7 23.4 1.0 N A:GLY72 4.7 29.1 1.0 CA A:ASP83 4.7 20.1 1.0 C A:HIS71 4.8 31.4 1.0 CD2 A:HIS46 4.8 21.7 1.0 O A:HOH418 4.9 35.7 1.0 CA A:HIS63 4.9 29.9 1.0 N A:HIS71 4.9 27.2 1.0 N A:ASP83 5.0 23.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn402 b:24.4 occ:1.00 ND1 B:HIS63 2.0 26.4 1.0 ND1 B:HIS71 2.0 19.3 1.0 OD1 B:ASP83 2.1 20.7 1.0 ND1 B:HIS80 2.2 18.2 1.0 CG B:ASP83 2.8 24.6 1.0 OD2 B:ASP83 2.9 22.2 1.0 CE1 B:HIS71 2.9 23.3 1.0 CE1 B:HIS63 2.9 26.4 1.0 CG B:HIS63 3.0 20.8 1.0 CE1 B:HIS80 3.1 22.5 1.0 CG B:HIS71 3.1 23.1 1.0 CG B:HIS80 3.2 20.9 1.0 CB B:HIS63 3.4 17.9 1.0 CB B:HIS80 3.6 24.1 1.0 CB B:HIS71 3.6 19.0 1.0 CA B:HIS71 3.9 23.4 1.0 NE2 B:HIS71 4.0 26.2 1.0 NE2 B:HIS63 4.0 24.1 1.0 O B:LYS136 4.1 28.3 1.0 CD2 B:HIS63 4.1 26.5 1.0 CD2 B:HIS71 4.2 29.9 1.0 CB B:ASP83 4.2 28.5 1.0 NE2 B:HIS80 4.2 22.9 1.0 CD2 B:HIS80 4.3 18.7 1.0 N B:HIS80 4.6 20.6 1.0 N B:GLY72 4.7 24.5 1.0 CA B:HIS80 4.7 19.1 1.0 CA B:ASP83 4.8 21.6 1.0 C B:HIS71 4.8 28.1 1.0 N B:HIS71 4.9 24.7 1.0 CD2 B:HIS46 4.9 27.9 1.0 N B:ASP83 4.9 20.6 1.0 CA B:HIS63 4.9 25.3 1.0

S.Yoshikawa, M.Kukimoto-Niino, K.Ito, L.Chen, Z.Q.Fu, J.Chrzas, B.C.Wang, M.Shirouzu, M.Urushitani, R.Takahashi, S.Yokoyama. Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G85R in Space Group P21 To Be Published.