Zinc in PDB 2z9l: Complex Structure of Sars-Cov 3C-Like Protease with JMF1586

The structure of Complex Structure of Sars-Cov 3C-Like Protease with JMF1586, PDB code: 2z9l was solved by C.C.Lee, A.H.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	51.920, 96.000, 67.590, 90.00, 103.62, 90.00
R / Rfree (%)	19.6 / 25.9

The binding sites of Zinc atom in the Complex Structure of Sars-Cov 3C-Like Protease with JMF1586 (pdb code 2z9l). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Complex Structure of Sars-Cov 3C-Like Protease with JMF1586, PDB code: 2z9l:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Complex Structure of Sars-Cov 3C-Like Protease with JMF1586


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Complex Structure of Sars-Cov 3C-Like Protease with JMF1586 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:42.7 occ:1.00 ZN A:DAZ701 0.0 42.7 1.0 N1 A:DAZ701 1.9 40.0 1.0 N2 A:DAZ701 2.0 42.2 1.0 NE2 A:HIS41 2.1 39.2 1.0 SG A:CYS145 2.3 37.0 1.0 CD2 A:HIS41 3.0 40.4 1.0 CE1 A:HIS41 3.1 38.8 1.0 CB A:CYS145 3.3 28.1 1.0 O A:HOH926 4.1 38.4 1.0 CG A:HIS41 4.1 40.6 1.0 O A:HIS164 4.1 33.3 1.0 ND1 A:HIS41 4.1 39.2 1.0 C1 A:DMS604 4.7 54.5 1.0 CA A:CYS145 4.8 26.6 1.0 CD2 A:LEU27 4.8 33.2 1.0

Zinc binding site 2 out of 2 in the Complex Structure of Sars-Cov 3C-Like Protease with JMF1586


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Complex Structure of Sars-Cov 3C-Like Protease with JMF1586 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn702 b:37.4 occ:1.00 ZN B:DAZ702 0.0 37.4 1.0 N2 B:DAZ702 2.0 34.0 1.0 N1 B:DAZ702 2.0 36.8 1.0 NE2 B:HIS41 2.1 31.4 1.0 SG B:CYS145 2.3 35.6 1.0 CE1 B:HIS41 3.0 28.8 1.0 CD2 B:HIS41 3.2 29.9 1.0 CB B:CYS145 3.2 29.9 1.0 O B:HOH814 3.9 38.4 1.0 O B:HIS164 4.1 27.6 1.0 ND1 B:HIS41 4.2 29.1 1.0 CG B:HIS41 4.3 28.6 1.0 CD2 B:LEU27 4.3 25.8 1.0 C1 B:DMS603 4.4 54.4 1.0 CA B:CYS145 4.6 28.9 1.0

C.C.Lee, C.J.Kuo, M.F.Hsu, P.H.Liang, J.M.Fang, J.J.Shie, A.H.Wang. Structural Basis of Mercury- and Zinc-Conjugated Complexes As Sars-Cov 3C-Like Protease Inhibitors. Febs Lett. V. 581 5454 2007.
ISSN: ISSN 0014-5793
PubMed: 17981158
DOI: 10.1016/J.FEBSLET.2007.10.048