Zinc in PDB 2z7u: Crystal Structure of H2O2 Treated Cu,Zn-Sod

All present enzymatic activity of Crystal Structure of H2O2 Treated Cu,Zn-Sod:
1.15.1.1;

The structure of Crystal Structure of H2O2 Treated Cu,Zn-Sod, PDB code: 2z7u was solved by S.Ito, T.Ishii, K.Uchida, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.44 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.106, 50.722, 149.456, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 23.8

The structure of Crystal Structure of H2O2 Treated Cu,Zn-Sod also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of H2O2 Treated Cu,Zn-Sod (pdb code 2z7u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of H2O2 Treated Cu,Zn-Sod, PDB code: 2z7u:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of H2O2 Treated Cu,Zn-Sod


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of H2O2 Treated Cu,Zn-Sod within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn300 b:59.8 occ:1.00 OD1 A:ASP81 2.0 40.2 1.0 ND1 A:HIS61 2.1 51.8 1.0 ND1 A:HIS78 2.3 46.4 1.0 ND1 A:HIS69 2.5 58.9 1.0 CG A:ASP81 2.9 41.0 1.0 CE1 A:HIS61 3.1 53.5 1.0 OD2 A:ASP81 3.1 41.5 1.0 CG A:HIS61 3.1 50.4 1.0 CE1 A:HIS78 3.2 46.1 1.0 CG A:HIS78 3.3 46.5 1.0 CG A:HIS69 3.4 57.7 1.0 CB A:HIS61 3.4 47.2 1.0 CE1 A:HIS69 3.5 59.1 1.0 CB A:HIS69 3.6 57.3 1.0 CB A:HIS78 3.6 45.4 1.0 O A:LYS134 3.8 86.3 1.0 CA A:HIS69 4.0 56.9 1.0 NE2 A:HIS61 4.2 54.9 1.0 CD2 A:HIS61 4.2 52.5 1.0 CB A:ASP81 4.3 40.4 1.0 NE2 A:HIS78 4.3 47.3 1.0 CD2 A:HIS78 4.4 46.4 1.0 CD2 A:HIS69 4.6 58.4 1.0 NE2 A:HIS69 4.6 59.3 1.0 CA A:ASP81 4.6 39.8 1.0 C A:LYS134 4.7 86.2 1.0 N A:ASP81 4.8 39.4 1.0 N A:HIS78 4.8 47.7 1.0 N A:GLY70 4.8 56.9 1.0 CA A:HIS78 4.8 46.3 1.0 O A:HOH312 4.8 53.0 1.0 C A:HIS69 4.9 57.1 1.0 CA A:HIS61 5.0 45.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of H2O2 Treated Cu,Zn-Sod


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of H2O2 Treated Cu,Zn-Sod within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn300 b:22.6 occ:1.00 ND1 B:HIS61 2.0 22.7 1.0 OD1 B:ASP81 2.1 21.0 1.0 ND1 B:HIS69 2.1 19.7 1.0 ND1 B:HIS78 2.2 19.7 1.0 CG B:ASP81 2.8 20.7 1.0 OD2 B:ASP81 2.9 18.6 1.0 CE1 B:HIS61 2.9 27.2 1.0 CE1 B:HIS69 3.0 20.5 1.0 CE1 B:HIS78 3.0 14.8 1.0 CG B:HIS61 3.0 25.3 1.0 CG B:HIS78 3.2 19.1 1.0 CG B:HIS69 3.2 20.2 1.0 CB B:HIS61 3.5 24.2 1.0 CB B:HIS78 3.5 18.4 1.0 CB B:HIS69 3.7 20.0 1.0 O B:LYS134 3.7 21.7 1.0 NE2 B:HIS61 4.0 26.3 1.0 CA B:HIS69 4.0 21.4 1.0 CD2 B:HIS61 4.1 25.3 1.0 NE2 B:HIS69 4.1 20.6 1.0 NE2 B:HIS78 4.2 17.6 1.0 CB B:ASP81 4.2 19.1 1.0 CD2 B:HIS78 4.2 16.9 1.0 CD2 B:HIS69 4.3 19.5 1.0 O B:HOH324 4.7 32.5 1.0 CA B:ASP81 4.7 20.1 1.0 C B:LYS134 4.7 22.4 1.0 N B:HIS78 4.7 21.5 1.0 CA B:HIS78 4.8 19.9 1.0 N B:ASP81 4.8 20.1 1.0 N B:GLY70 4.8 22.0 1.0 CA B:HIS61 5.0 24.7 1.0

S.Ito, T.Ishii, K.Uchida. Crystal Structures of H2O2-Treated Cu,Zn-Superoxide Dismutase To Be Published.