Atomistry » Zinc » PDB 2z45-2zem » 2z72
Atomistry »
  Zinc »
    PDB 2z45-2zem »
      2z72 »

Zinc in PDB 2z72: New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom

Enzymatic activity of New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom

All present enzymatic activity of New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom:
3.1.3.48;

Protein crystallography data

The structure of New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom, PDB code: 2z72 was solved by H.Tsuruta, B.Mikami, C.Yamamoto, H.Yamagata, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 8.00 / 1.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 55.565, 77.306, 81.029, 90.00, 90.00, 90.00
R / Rfree (%) 11 / 16.1

Zinc Binding Sites:

The binding sites of Zinc atom in the New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom (pdb code 2z72). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom, PDB code: 2z72:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2z72

Go back to Zinc Binding Sites List in 2z72
Zinc binding site 1 out of 2 in the New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:9.9
occ:1.00
O A:HOH1269 2.0 11.7 1.0
OD1 A:ASP78 2.0 9.0 1.0
NE2 A:HIS80 2.0 9.0 1.0
O A:HOH1267 2.1 11.3 1.0
OD1 A:ASP114 2.2 9.2 1.0
CE1 A:HIS80 3.0 8.9 1.0
CD2 A:HIS80 3.0 9.3 1.0
CG A:ASP78 3.1 8.6 1.0
CG A:ASP114 3.2 8.3 1.0
ZN A:ZN402 3.2 9.4 1.0
CB A:ASP114 3.5 8.3 1.0
CB A:ASP78 3.7 8.9 1.0
O A:HOH1259 4.1 23.0 1.0
ND1 A:HIS80 4.1 9.4 1.0
OD2 A:ASP78 4.2 9.5 1.0
O A:HIS286 4.2 11.8 1.0
CE1 A:HIS207 4.2 8.7 1.0
NE2 A:HIS207 4.2 8.3 1.0
CG A:HIS80 4.2 8.7 1.0
OD1 A:ASP304 4.2 10.7 1.0
O A:HOH1587 4.3 17.8 1.0
OD2 A:ASP114 4.4 8.9 1.0
CA A:HIS286 4.4 10.5 1.0
CD2 A:HIS150 4.4 9.3 1.0
CA A:ASP78 4.4 8.5 1.0
C A:HIS286 4.7 11.5 1.0
NE2 A:HIS150 4.8 10.6 1.0
OD1 A:ASN149 4.8 9.4 1.0
ND1 A:HIS286 4.9 10.8 1.0
N A:HIS286 4.9 10.6 1.0
NE A:ARG118 5.0 31.8 0.5
CA A:ASP114 5.0 7.7 1.0

Zinc binding site 2 out of 2 in 2z72

Go back to Zinc Binding Sites List in 2z72
Zinc binding site 2 out of 2 in the New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of New Structure of Cold-Active Protein Tyrosine Phosphatase at 1.1 Angstrom within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:9.4
occ:1.00
O A:HOH1269 2.0 11.7 1.0
NE2 A:HIS207 2.0 8.3 1.0
OD1 A:ASN149 2.1 9.4 1.0
ND1 A:HIS286 2.1 10.8 1.0
OD1 A:ASP114 2.3 9.2 1.0
CD2 A:HIS207 3.0 8.2 1.0
CE1 A:HIS207 3.0 8.7 1.0
CE1 A:HIS286 3.1 12.4 1.0
CG A:HIS286 3.1 11.2 1.0
CG A:ASN149 3.1 8.8 1.0
ZN A:ZN401 3.2 9.9 1.0
CG A:ASP114 3.2 8.3 1.0
O A:HOH1587 3.4 17.8 1.0
CB A:HIS286 3.5 10.9 1.0
CA A:HIS286 3.6 10.5 1.0
ND2 A:ASN149 3.6 10.7 1.0
OD2 A:ASP114 3.6 8.9 1.0
OD1 A:ASP78 3.7 9.0 1.0
O A:HIS286 4.1 11.8 1.0
CD2 A:HIS150 4.1 9.3 1.0
ND1 A:HIS207 4.1 8.3 1.0
CG A:HIS207 4.2 7.9 1.0
CD2 A:HIS286 4.2 13.0 1.0
NE2 A:HIS286 4.3 14.9 1.0
C A:HIS286 4.3 11.5 1.0
CB A:ASN149 4.4 9.1 1.0
CB A:ASP114 4.4 8.3 1.0
N A:ASN149 4.5 8.3 1.0
O A:THR255 4.6 10.4 1.0
N A:HIS286 4.6 10.6 1.0
NE2 A:HIS150 4.7 10.6 1.0
O A:HOH1267 4.8 11.3 1.0
CG A:ASP78 4.9 8.6 1.0
NE2 A:HIS80 4.9 9.0 1.0
CA A:ASN149 4.9 8.2 1.0

Reference:

H.Tsuruta, B.Mikami, C.Yamamoto, H.Yamagata. The Role of Group Bulkiness in the Catalytic Activity of Psychrophile Cold-Active Protein Tyrosine Phosphatase Febs J. V. 275 4317 2008.
ISSN: ISSN 1742-464X
PubMed: 18647345
DOI: 10.1111/J.1742-4658.2008.06575.X
Page generated: Wed Dec 16 04:04:29 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy