Zinc in PDB 2z00: Crystal Structure of Dihydroorotase From Thermus Thermophilus

All present enzymatic activity of Crystal Structure of Dihydroorotase From Thermus Thermophilus:
3.5.2.3;

The structure of Crystal Structure of Dihydroorotase From Thermus Thermophilus, PDB code: 2z00 was solved by M.Kanagawa, S.Baba, S.Kuramitsu, S.Yokoyama, G.Kawai, G.Sampei, Rikenstructural Genomics/Proteomics Initiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.85 / 2.42
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	129.937, 129.937, 209.906, 90.00, 90.00, 120.00
R / Rfree (%)	18.8 / 19.2

The binding sites of Zinc atom in the Crystal Structure of Dihydroorotase From Thermus Thermophilus (pdb code 2z00). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Dihydroorotase From Thermus Thermophilus, PDB code: 2z00:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Dihydroorotase From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Dihydroorotase From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1004 b:1.4 occ:0.42 NE2 A:HIS55 2.1 15.5 1.0 NE2 A:HIS57 2.2 20.2 1.0 OD2 A:ASP147 2.2 23.4 1.0 OD2 A:ASP306 2.4 16.1 1.0 CE1 A:HIS55 2.8 14.5 1.0 CE1 A:HIS57 3.1 18.6 1.0 CD2 A:HIS55 3.2 14.1 1.0 CD2 A:HIS57 3.3 18.5 1.0 CG A:ASP147 3.3 22.4 1.0 ZN A:ZN1006 3.3 1.4 0.4 CG A:ASP306 3.3 15.4 1.0 O A:HOH1125 3.4 42.1 1.0 OD1 A:ASP147 3.6 22.8 1.0 OD1 A:ASP306 3.7 16.2 1.0 ND1 A:HIS55 4.0 15.9 1.0 CG A:HIS55 4.2 14.4 1.0 ND1 A:HIS57 4.3 15.8 1.0 CG A:HIS57 4.4 17.9 1.0 CB A:ASP306 4.5 15.8 1.0 CD2 A:HIS233 4.6 29.7 1.0 CB A:ASP147 4.6 22.1 1.0 CA A:ASP306 4.7 15.3 1.0 NE2 A:HIS233 4.8 33.6 1.0 SE A:MSE87 4.8 40.3 1.0 O A:HOH1009 4.8 4.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Dihydroorotase From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Dihydroorotase From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1006 b:1.4 occ:0.40 OD1 A:ASP147 2.1 22.8 1.0 ND1 A:HIS174 2.2 18.5 1.0 NE2 A:HIS233 2.4 33.6 1.0 CE1 A:HIS174 2.9 19.9 1.0 CG A:ASP147 3.0 22.4 1.0 CD2 A:HIS233 3.2 29.7 1.0 O A:HOH1125 3.2 42.1 1.0 OD2 A:ASP147 3.3 23.4 1.0 ZN A:ZN1004 3.3 1.4 0.4 CE1 A:HIS233 3.3 35.0 1.0 CG A:HIS174 3.4 17.1 1.0 CB A:HIS174 3.9 15.1 1.0 CE1 A:HIS55 4.1 14.5 1.0 NE2 A:HIS174 4.1 17.1 1.0 O A:ALA279 4.2 18.6 1.0 N A:GLY148 4.2 27.2 1.0 O A:HOH1183 4.2 40.2 1.0 CG A:HIS233 4.3 28.6 1.0 ND1 A:HIS233 4.4 33.0 1.0 CD2 A:HIS174 4.4 16.8 1.0 NE2 A:HIS55 4.4 15.5 1.0 CB A:ASP147 4.4 22.1 1.0 OD1 A:ASP306 4.6 16.2 1.0 CA A:GLY148 4.7 26.8 1.0 CA A:HIS174 4.7 16.0 1.0 OD2 A:ASP306 4.8 16.1 1.0 C A:ASP147 4.8 25.4 1.0 CA A:ASP147 4.9 22.4 1.0 OE1 A:GLN232 4.9 22.2 1.0 CG A:ASP306 5.0 15.4 1.0

M.Kanagawa, S.Baba, S.Kuramitsu, S.Yokoyama, G.Kawai, G.Sampei. Crystal Structure of Dihydroorotase From Thermus Thermophilus To Be Published.