Zinc in PDB 2yuu: Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta

All present enzymatic activity of Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta:
2.7.11.13;

The binding sites of Zinc atom in the Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta (pdb code 2yuu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta, PDB code: 2yuu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:0.0 occ:1.00 ND1 A:HIS18 2.1 0.0 1.0 SG A:CYS51 2.3 0.0 1.0 SG A:CYS67 2.4 0.0 1.0 SG A:CYS48 2.4 0.0 1.0 CE1 A:HIS18 2.7 0.0 1.0 HE1 A:HIS18 2.7 0.0 1.0 H A:CYS51 3.2 0.0 1.0 CG A:HIS18 3.3 0.0 1.0 CB A:CYS48 3.3 0.0 1.0 HB3 A:CYS48 3.3 0.0 1.0 HB2 A:GLN50 3.3 0.0 1.0 HB2 A:CYS67 3.3 0.0 1.0 HB2 A:CYS48 3.3 0.0 1.0 HB3 A:CYS51 3.4 0.0 1.0 CB A:CYS67 3.4 0.0 1.0 CB A:CYS51 3.5 0.0 1.0 H A:GLU19 3.6 0.0 1.0 HA A:CYS67 3.6 0.0 1.0 HA A:HIS18 3.6 0.0 1.0 HB3 A:HIS18 3.6 0.0 1.0 CB A:HIS18 3.9 0.0 1.0 N A:CYS51 3.9 0.0 1.0 NE2 A:HIS18 3.9 0.0 1.0 H A:THR68 4.0 0.0 1.0 HB3 A:ALA53 4.1 0.0 1.0 CA A:CYS67 4.1 0.0 1.0 CD2 A:HIS18 4.2 0.0 1.0 CA A:HIS18 4.3 0.0 1.0 CA A:CYS51 4.3 0.0 1.0 HB2 A:CYS51 4.3 0.0 1.0 HB3 A:CYS67 4.3 0.0 1.0 CB A:GLN50 4.4 0.0 1.0 H A:GLY69 4.4 0.0 1.0 N A:GLU19 4.5 0.0 1.0 H A:GLN50 4.5 0.0 1.0 HE2 A:HIS18 4.7 0.0 1.0 CA A:CYS48 4.7 0.0 1.0 H A:ASN52 4.7 0.0 1.0 HB3 A:GLN50 4.7 0.0 1.0 N A:THR68 4.8 0.0 1.0 H A:ALA53 4.8 0.0 1.0 HG3 A:GLN50 4.8 0.0 1.0 HE1 A:PHE20 4.8 0.0 1.0 OE1 A:GLU19 4.9 0.0 1.0 C A:GLN50 4.9 0.0 1.0 HB2 A:GLU19 4.9 0.0 1.0 HB2 A:HIS18 4.9 0.0 1.0 C A:HIS18 5.0 0.0 1.0 CE1 A:PHE20 5.0 0.0 1.0 C A:CYS67 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:0.0 occ:1.00 ND1 A:HIS56 2.0 0.0 1.0 SG A:CYS59 2.2 0.0 1.0 SG A:CYS31 2.3 0.0 1.0 SG A:CYS34 2.4 0.0 1.0 H A:CYS34 2.7 0.0 1.0 CE1 A:HIS56 2.8 0.0 1.0 H A:HIS56 2.8 0.0 1.0 HE1 A:HIS56 3.0 0.0 1.0 CG A:HIS56 3.0 0.0 1.0 HB2 A:HIS56 3.1 0.0 1.0 HB2 A:CYS59 3.2 0.0 1.0 HB A:VAL33 3.2 0.0 1.0 HB2 A:CYS31 3.3 0.0 1.0 CB A:CYS31 3.3 0.0 1.0 CB A:CYS59 3.3 0.0 1.0 HB3 A:CYS31 3.4 0.0 1.0 HB3 A:CYS34 3.4 0.0 1.0 CB A:CYS34 3.4 0.0 1.0 H A:LYS35 3.5 0.0 1.0 CB A:HIS56 3.5 0.0 1.0 N A:CYS34 3.5 0.0 1.0 HB3 A:CYS59 3.6 0.0 1.0 N A:HIS56 3.7 0.0 1.0 NE2 A:HIS56 3.9 0.0 1.0 H A:ASP36 3.9 0.0 1.0 HA A:ILE55 4.0 0.0 1.0 CD2 A:HIS56 4.0 0.0 1.0 CA A:CYS34 4.0 0.0 1.0 HB A:ILE55 4.1 0.0 1.0 HB2 A:ASP36 4.1 0.0 1.0 H A:VAL33 4.2 0.0 1.0 N A:LYS35 4.2 0.0 1.0 CA A:HIS56 4.2 0.0 1.0 CB A:VAL33 4.3 0.0 1.0 HB2 A:CYS34 4.4 0.0 1.0 HG21 A:VAL38 4.4 0.0 1.0 HB3 A:HIS56 4.5 0.0 1.0 HG13 A:VAL33 4.5 0.0 1.0 C A:ILE55 4.6 0.0 1.0 C A:CYS34 4.6 0.0 1.0 C A:VAL33 4.6 0.0 1.0 CA A:ILE55 4.7 0.0 1.0 CA A:CYS59 4.7 0.0 1.0 H A:CYS59 4.7 0.0 1.0 CA A:CYS31 4.7 0.0 1.0 HE2 A:HIS56 4.7 0.0 1.0 N A:VAL33 4.8 0.0 1.0 H A:SER32 4.8 0.0 1.0 CA A:VAL33 4.8 0.0 1.0 N A:ASP36 4.8 0.0 1.0 CG1 A:VAL33 4.9 0.0 1.0 HG22 A:VAL38 4.9 0.0 1.0 CB A:ILE55 4.9 0.0 1.0 HA A:HIS56 4.9 0.0 1.0 HA A:CYS59 4.9 0.0 1.0 HA A:CYS34 5.0 0.0 1.0 HG21 A:VAL33 5.0 0.0 1.0 HD2 A:HIS56 5.0 0.0 1.0

H.Abe, K.Miyamoto, N.Tochio, K.Saito, A.Sasagawa, S.Koshiba, M.Inoue, T.Kigawa, S.Yokoyama. Solution Structure of the First Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C, Delta To Be Published.