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Atomistry » Zinc » PDB 2wfq-2wwn » 2wwj | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 2wfq-2wwn » 2wwj » |
Zinc in PDB 2wwj: Structure of JMJD2A Complexed with Inhibitor 10AEnzymatic activity of Structure of JMJD2A Complexed with Inhibitor 10A
All present enzymatic activity of Structure of JMJD2A Complexed with Inhibitor 10A:
1.14.11.27; Protein crystallography data
The structure of Structure of JMJD2A Complexed with Inhibitor 10A, PDB code: 2wwj
was solved by
N.R.Rose,
I.J.Clifton,
U.Oppermann,
M.A.Mcdonough,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wwj:
The structure of Structure of JMJD2A Complexed with Inhibitor 10A also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of JMJD2A Complexed with Inhibitor 10A
(pdb code 2wwj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of JMJD2A Complexed with Inhibitor 10A, PDB code: 2wwj: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2wwjGo back to Zinc Binding Sites List in 2wwj
Zinc binding site 1 out
of 2 in the Structure of JMJD2A Complexed with Inhibitor 10A
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2wwjGo back to Zinc Binding Sites List in 2wwj
Zinc binding site 2 out
of 2 in the Structure of JMJD2A Complexed with Inhibitor 10A
Mono view Stereo pair view
Reference:
N.R.Rose,
E.C.Woon,
G.L.Kingham,
O.N.King,
J.Mecinovic,
I.J.Clifton,
S.S.Ng,
J.Talib-Hardy,
U.Oppermann,
M.A.Mcdonough,
C.J.Schofield.
Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches. J. Med. Chem. V. 53 1810 2010.
Page generated: Thu Oct 17 05:02:47 2024
ISSN: ISSN 1520-4804 PubMed: 20088513 DOI: 10.1021/JM901680B |
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