Atomistry » Zinc » PDB 2wfq-2wwn » 2wta
Atomistry »
  Zinc »
    PDB 2wfq-2wwn »
      2wta »

Zinc in PDB 2wta: Acinetobacter Baumanii Nicotinamidase Pyrazinamidease

Enzymatic activity of Acinetobacter Baumanii Nicotinamidase Pyrazinamidease

All present enzymatic activity of Acinetobacter Baumanii Nicotinamidase Pyrazinamidease:
3.5.1.19;

Protein crystallography data

The structure of Acinetobacter Baumanii Nicotinamidase Pyrazinamidease, PDB code: 2wta was solved by P.K.Fyfe, V.A.Rao, A.Zemla, S.Cameron, W.N.Hunter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.54 / 1.70
Space group I 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 50.688, 46.507, 107.602, 90.00, 101.97, 90.00
R / Rfree (%) 14.748 / 17.661

Other elements in 2wta:

The structure of Acinetobacter Baumanii Nicotinamidase Pyrazinamidease also contains other interesting chemical elements:

Arsenic (As) 1 atom
Chlorine (Cl) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Acinetobacter Baumanii Nicotinamidase Pyrazinamidease (pdb code 2wta). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Acinetobacter Baumanii Nicotinamidase Pyrazinamidease, PDB code: 2wta:

Zinc binding site 1 out of 1 in 2wta

Go back to Zinc Binding Sites List in 2wta
Zinc binding site 1 out of 1 in the Acinetobacter Baumanii Nicotinamidase Pyrazinamidease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Acinetobacter Baumanii Nicotinamidase Pyrazinamidease within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1215

b:24.1
occ:1.00
OD2 A:ASP54 2.1 19.4 1.0
NE2 A:HIS56 2.1 12.7 1.0
NE2 A:HIS89 2.2 17.9 1.0
N5 A:VGL1216 2.2 22.6 0.8
O A:HOH2201 2.3 21.5 1.0
O A:HOH2202 2.3 23.9 1.0
C4 A:VGL1216 3.0 25.6 0.8
CE1 A:HIS89 3.0 17.4 1.0
CG A:ASP54 3.1 18.7 1.0
CE1 A:HIS56 3.1 14.8 1.0
CD2 A:HIS56 3.1 13.3 1.0
C6 A:VGL1216 3.2 26.3 0.8
CD2 A:HIS89 3.2 16.4 1.0
OD1 A:ASP54 3.4 22.0 1.0
OD1 A:ASP121 4.1 20.4 1.0
ND1 A:HIS89 4.2 15.7 1.0
ND1 A:HIS56 4.2 12.4 1.0
CG A:HIS56 4.3 12.7 1.0
C3 A:VGL1216 4.3 25.6 0.8
CG A:HIS89 4.3 15.7 1.0
CB A:ASP54 4.4 15.0 1.0
OG A:SER62 4.5 15.9 1.0
C1 A:VGL1216 4.5 26.9 0.8
CZ A:PHE21 4.6 19.1 1.0
OD2 A:ASP121 4.6 18.4 1.0
CG A:ASP121 4.8 19.2 1.0
N2 A:VGL1216 4.9 28.4 0.8

Reference:

P.K.Fyfe, V.A.Rao, A.Zemla, S.Cameron, W.N.Hunter. Specificity and Mechanism of Acinetobacter Baumanii Nicotinamidase: Implications For Activation of the Front-Line Tuberculosis Drug Pyrazinamide. Angew.Chem.Int.Ed.Engl. V. 48 9176 2009.
ISSN: ISSN 1433-7851
PubMed: 19859929
DOI: 10.1002/ANIE.200903407
Page generated: Wed Dec 16 03:58:26 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy