Zinc in PDB 2vz5: Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3

The structure of Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3, PDB code: 2vz5 was solved by J.W.Murray, N.Shafqat, W.Yue, E.Pilka, C.Johannsson, E.Salah, C.Cooper, J.M.Elkins, A.C.Pike, A.Roos, P.Filippakopoulos, F.Von Delft, M.Wickstroem, C.Bountra, A.M.Edwards, C.H.Arrowsmith, U.Oppermann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.82 / 1.74
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	59.813, 59.813, 121.289, 90.00, 90.00, 120.00
R / Rfree (%)	17.4 / 22.6

The structure of Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (pdb code 2vz5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3, PDB code: 2vz5:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1131 b:27.8 occ:1.00 N1 A:IMD1130 1.2 8.8 1.0 OE2 A:GLU62 2.0 24.6 1.0 OE2 A:GLU67 2.1 26.2 1.0 N3 A:IMD1129 2.1 32.2 1.0 C5 A:IMD1130 2.3 33.1 1.0 C2 A:IMD1130 2.3 40.7 1.0 OE1 A:GLU62 2.6 23.7 1.0 CD A:GLU62 2.6 24.1 1.0 C4 A:IMD1129 2.7 42.1 1.0 CD A:GLU67 2.7 24.7 1.0 OE1 A:GLU67 2.7 24.8 1.0 C2 A:IMD1129 3.4 40.4 1.0 N3 A:IMD1130 3.4 40.9 1.0 C4 A:IMD1130 3.4 34.4 1.0 H A:GLY63 3.8 12.3 1.0 C5 A:IMD1129 4.0 36.8 1.0 CG A:GLU62 4.1 17.1 1.0 CG A:GLU67 4.1 21.8 1.0 O A:HOH2058 4.2 49.4 1.0 HA A:GLU62 4.2 13.0 1.0 N1 A:IMD1129 4.3 37.0 1.0 HG3 A:GLU62 4.3 12.1 1.0 O A:HOH2055 4.3 17.1 1.0 HG3 A:GLU67 4.4 17.2 1.0 N A:GLY63 4.4 16.0 1.0 HG2 A:GLU67 4.5 17.2 1.0 HG2 A:GLU62 4.5 12.1 1.0 HA2 A:GLY63 4.7 12.9 1.0 CA A:GLU62 4.9 19.6 1.0 CB A:GLU62 4.9 18.6 1.0 HB3 A:GLU67 4.9 16.9 1.0

Zinc binding site 2 out of 2 in the Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Pdz Domain of TAX1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1132 b:74.0 occ:1.00 NE2 A:HIS19 2.2 42.1 1.0 CD2 A:HIS19 3.1 37.6 1.0 HD2 A:HIS19 3.2 23.0 1.0 CE1 A:HIS19 3.3 42.1 1.0 HG23 A:VAL104 3.5 22.1 1.0 HE1 A:HIS19 3.5 23.4 1.0 OE2 A:GLU17 3.8 28.4 1.0 HG21 A:VAL104 4.1 22.1 1.0 CG2 A:VAL104 4.2 40.4 1.0 CG A:HIS19 4.3 32.8 1.0 ND1 A:HIS19 4.3 41.6 1.0 HG12 A:VAL104 4.5 21.5 1.0 HG22 A:VAL104 4.7 22.1 1.0 HH21 A:ARG106 4.8 31.5 1.0 HH22 A:ARG106 4.9 31.5 1.0 CD A:GLU17 5.0 33.0 1.0

J.W.Murray, N.Shafqat, W.Yue, E.Pilka, C.Johannsson, E.Salah, C.Cooper, J.M.Elkins, A.C.Pike, A.Roos, P.Filippakopoulos, F.Von Delft, M.Wickstroem, C.Bountra, A.M.Edwards, C.H.Arrowsmith, U.Oppermann. The Structure of the Pdz Domain of TAX1BP To Be Published.