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Atomistry » Zinc » PDB 2rv3-2v1c » 2v0c | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 2rv3-2v1c » 2v0c » |
Zinc in PDB 2v0c: Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing SiteProtein crystallography data
The structure of Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site, PDB code: 2v0c
was solved by
F.Rock,
W.Mao,
A.Yaremchuk,
M.Tukalo,
T.Crepin,
H.Zhou,
Y.Zhang,
V.Hernandez,
T.Akama,
S.Baker,
J.Plattner,
L.Shapiro,
S.A.Martinis,
S.J.Benkovic,
S.Cusack,
M.R.K.Alley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2v0c:
The structure of Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site
(pdb code 2v0c). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site, PDB code: 2v0c: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2v0cGo back to Zinc Binding Sites List in 2v0c
Zinc binding site 1 out
of 2 in the Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2v0cGo back to Zinc Binding Sites List in 2v0c
Zinc binding site 2 out
of 2 in the Leucyl-Trna Synthetase From Thermus Thermophilus Complexed with A Sulphamoyl Analogue of Leucyl-Adenylate in the Synthetic Site and An Adduct of Amp with 5-Fluoro-1,3- Dihydro-1-Hydroxy-2,1-Benzoxaborole (AN2690) in the Editing Site
Mono view Stereo pair view
Reference:
F.Rock,
W.Mao,
A.Yaremchuk,
M.Tukalo,
T.Crepin,
H.Zhou,
Y.Zhang,
V.Hernandez,
T.Akama,
S.Baker,
J.Plattner,
L.Shapiro,
S.A.Martinis,
S.J.Benkovic,
S.Cusack,
M.R.K.Alley.
An Antifungal Agent Inhibits An Aminoacyl-Trna Synthetase By Trapping Trna in the Editing Site. Science V. 316 1759 2007.
Page generated: Thu Oct 17 04:04:09 2024
ISSN: ISSN 0036-8075 PubMed: 17588934 DOI: 10.1126/SCIENCE.1142189 |
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