Zinc in PDB 2rc4: Crystal Structure of the Hat Domain of the Human Moz Protein

All present enzymatic activity of Crystal Structure of the Hat Domain of the Human Moz Protein:
2.3.1.48;

The structure of Crystal Structure of the Hat Domain of the Human Moz Protein, PDB code: 2rc4 was solved by M.A.Holbert, T.Sikorski, D.Snowflack, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 3.00
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	109.200, 109.200, 144.779, 90.00, 90.00, 90.00
R / Rfree (%)	27.6 / 28.3

The binding sites of Zinc atom in the Crystal Structure of the Hat Domain of the Human Moz Protein (pdb code 2rc4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Hat Domain of the Human Moz Protein, PDB code: 2rc4:

Zinc binding site 1 out of 1 in the Crystal Structure of the Hat Domain of the Human Moz Protein


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Hat Domain of the Human Moz Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:85.8 occ:1.00 SG A:CYS543 2.0 57.9 1.0 SG A:CYS560 2.2 86.5 1.0 SG A:CYS540 2.4 59.4 1.0 NE2 A:HIS556 2.6 79.0 1.0 CB A:CYS543 3.2 58.0 1.0 CE1 A:HIS556 3.3 78.9 1.0 CB A:CYS540 3.5 59.2 1.0 CB A:CYS560 3.7 86.0 1.0 CD2 A:HIS556 3.8 80.1 1.0 N A:CYS543 3.8 57.9 1.0 CA A:CYS543 4.0 58.3 1.0 SD A:MET557 4.4 85.3 1.0 ND1 A:HIS556 4.5 80.1 1.0 CA A:CYS560 4.8 86.0 1.0 CG A:HIS556 4.8 81.4 1.0 C A:CYS543 4.8 58.8 1.0 CA A:CYS540 4.9 59.1 1.0

M.A.Holbert, T.Sikorski, J.Carten, D.Snowflack, S.Hodawadekar, R.Marmorstein. The Human Monocytic Leukemia Zinc Finger Histone Acetyltransferase Domain Contains Dna-Binding Activity Implicated in Chromatin Targeting. J.Biol.Chem. V. 282 36603 2007.
ISSN: ISSN 0021-9258
PubMed: 17925393
DOI: 10.1074/JBC.M705812200