Zinc in PDB 2r2v: Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil

The structure of Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil, PDB code: 2r2v was solved by J.Liu, M.Lu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	51.71 / 1.90
Space group	P 43
Cell size a, b, c (Å), α, β, γ (°)	51.696, 51.696, 99.793, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 24

The binding sites of Zinc atom in the Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil (pdb code 2r2v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil, PDB code: 2r2v:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn35 b:29.1 occ:1.00 NE2 C:HIS19 2.0 25.4 1.0 O3 C:CIT37 2.0 36.2 1.0 OE2 C:GLU23 2.2 26.2 1.0 O5 C:CIT37 2.2 30.3 1.0 O G:HOH44 2.2 32.4 1.0 O7 C:CIT37 2.2 33.6 1.0 C6 C:CIT37 2.9 35.2 1.0 C3 C:CIT37 3.0 36.3 1.0 CE1 C:HIS19 3.0 27.2 1.0 CD2 C:HIS19 3.0 23.2 1.0 C5 C:CIT37 3.0 38.3 1.0 CD C:GLU23 3.1 25.2 1.0 CG C:GLU23 3.5 24.2 1.0 C4 C:CIT37 3.5 37.8 1.0 NE2 G:HIS19 4.0 29.6 1.0 O6 C:CIT37 4.1 35.8 1.0 ND1 C:HIS19 4.1 25.0 1.0 O4 C:CIT37 4.1 40.5 1.0 CG C:HIS19 4.1 23.5 1.0 OE1 C:GLU23 4.2 24.2 1.0 O3 G:CIT35 4.2 30.8 1.0 NZ D:LYS9 4.3 36.2 1.0 O1 C:CIT37 4.3 40.9 1.0 CE1 G:HIS19 4.3 30.7 1.0 C2 C:CIT37 4.4 38.0 1.0 C1 C:CIT37 4.7 40.0 1.0 O C:HOH50 4.9 44.4 1.0 CE D:LYS9 4.9 37.0 1.0 CB C:GLU23 5.0 23.9 1.0 NZ D:LYS16 5.0 31.1 1.0

Zinc binding site 2 out of 2 in the Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn35 b:24.8 occ:1.00 OE2 D:GLU23 2.0 24.4 1.0 NE2 D:HIS19 2.1 23.9 1.0 O G:HOH37 2.1 27.2 1.0 O3 D:CIT38 2.2 31.9 1.0 O7 D:CIT38 2.3 28.3 1.0 O5 D:CIT38 2.3 25.1 1.0 C6 D:CIT38 3.0 29.8 1.0 CD D:GLU23 3.0 23.0 1.0 C3 D:CIT38 3.0 30.9 1.0 CE1 D:HIS19 3.0 24.5 1.0 CD2 D:HIS19 3.1 21.5 1.0 C5 D:CIT38 3.2 33.5 1.0 CG D:GLU23 3.4 22.2 1.0 C4 D:CIT38 3.6 31.9 1.0 NZ C:LYS9 4.0 31.0 1.0 OE1 D:GLU23 4.1 21.6 1.0 ND1 D:HIS19 4.1 21.6 1.0 CG D:HIS19 4.2 21.5 1.0 O6 D:CIT38 4.2 31.0 1.0 O4 G:CIT36 4.2 30.1 1.0 O4 D:CIT38 4.3 34.0 1.0 O1 D:CIT38 4.3 31.1 1.0 C2 D:CIT38 4.4 30.6 1.0 CE C:LYS9 4.7 31.4 1.0 C1 D:CIT38 4.8 32.8 1.0 NZ C:LYS16 4.9 28.2 1.0 CB D:GLU23 4.9 21.4 1.0 O C:HOH49 5.0 35.3 1.0

J.Liu, Q.Zheng, Y.Deng, Q.Li, N.R.Kallenbach, M.Lu. Conformational Specificity of the Lac Repressor Coiled-Coil Tetramerization Domain. Biochemistry V. 46 14951 2007.
ISSN: ISSN 0006-2960
PubMed: 18052214
DOI: 10.1021/BI701930D