Zinc in PDB 2kyu: The Solution Structure of the PHD3 Finger of Mll

The binding sites of Zinc atom in the The Solution Structure of the PHD3 Finger of Mll (pdb code 2kyu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Solution Structure of the PHD3 Finger of Mll, PDB code: 2kyu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Solution Structure of the PHD3 Finger of Mll


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Solution Structure of the PHD3 Finger of Mll within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn81 b:0.0 occ:1.00 H A:ASP12 1.7 0.0 1.0 ND1 A:HIS35 2.1 0.0 1.0 SG A:CYS8 2.3 0.0 1.0 SG A:CYS11 2.3 0.0 1.0 SG A:CYS38 2.4 0.0 1.0 HB2 A:HIS35 2.5 0.0 1.0 N A:ASP12 2.6 0.0 1.0 H A:CYS11 2.8 0.0 1.0 HA A:ASP12 2.8 0.0 1.0 HB3 A:CYS38 2.9 0.0 1.0 CG A:HIS35 2.9 0.0 1.0 CB A:HIS35 3.1 0.0 1.0 CB A:CYS38 3.1 0.0 1.0 CE1 A:HIS35 3.2 0.0 1.0 HB3 A:CYS8 3.3 0.0 1.0 HB2 A:CYS38 3.3 0.0 1.0 CA A:ASP12 3.3 0.0 1.0 CB A:CYS8 3.4 0.0 1.0 HB2 A:LEU10 3.4 0.0 1.0 HB3 A:HIS35 3.4 0.0 1.0 N A:CYS11 3.4 0.0 1.0 HE1 A:HIS35 3.5 0.0 1.0 H A:LYS13 3.5 0.0 1.0 C A:CYS11 3.6 0.0 1.0 CB A:CYS11 3.6 0.0 1.0 HG A:LEU10 3.7 0.0 1.0 HB2 A:CYS8 3.7 0.0 1.0 CA A:CYS11 3.8 0.0 1.0 HB3 A:ASP12 4.0 0.0 1.0 H A:HIS35 4.1 0.0 1.0 CD2 A:HIS35 4.2 0.0 1.0 HB2 A:CYS11 4.2 0.0 1.0 NE2 A:HIS35 4.3 0.0 1.0 N A:LYS13 4.3 0.0 1.0 H A:LEU10 4.3 0.0 1.0 CB A:LEU10 4.3 0.0 1.0 CB A:ASP12 4.3 0.0 1.0 C A:ASP12 4.3 0.0 1.0 HB3 A:CYS11 4.4 0.0 1.0 CG A:LEU10 4.4 0.0 1.0 CA A:HIS35 4.5 0.0 1.0 C A:LEU10 4.5 0.0 1.0 HD11 A:LEU10 4.5 0.0 1.0 CA A:CYS38 4.6 0.0 1.0 N A:HIS35 4.7 0.0 1.0 O A:CYS11 4.7 0.0 1.0 CA A:CYS8 4.8 0.0 1.0 HE2 A:MET24 4.8 0.0 1.0 CA A:LEU10 4.8 0.0 1.0 HA A:CYS11 4.8 0.0 1.0 H A:CYS38 4.9 0.0 1.0 CD1 A:LEU10 4.9 0.0 1.0 N A:LEU10 4.9 0.0 1.0 HB2 A:ASP12 4.9 0.0 1.0 HA A:HIS35 4.9 0.0 1.0 HD12 A:LEU10 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the The Solution Structure of the PHD3 Finger of Mll


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Solution Structure of the PHD3 Finger of Mll within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn82 b:0.0 occ:1.00 SG A:CYS30 2.2 0.0 1.0 SG A:CYS63 2.3 0.0 1.0 SG A:CYS27 2.3 0.0 1.0 SG A:CYS60 2.3 0.0 1.0 H A:CYS30 2.7 0.0 1.0 HB2 A:CYS63 2.8 0.0 1.0 H A:CYS60 2.9 0.0 1.0 CB A:CYS63 3.1 0.0 1.0 CB A:CYS27 3.3 0.0 1.0 HB2 A:CYS27 3.4 0.0 1.0 HB3 A:LYS29 3.4 0.0 1.0 HB3 A:CYS27 3.4 0.0 1.0 HB3 A:CYS60 3.5 0.0 1.0 CB A:CYS60 3.5 0.0 1.0 N A:CYS30 3.5 0.0 1.0 CB A:CYS30 3.5 0.0 1.0 H A:CYS63 3.6 0.0 1.0 HB3 A:CYS30 3.6 0.0 1.0 HB3 A:CYS63 3.8 0.0 1.0 N A:CYS60 3.8 0.0 1.0 HG23 A:THR59 3.8 0.0 1.0 H A:ARG32 3.8 0.0 1.0 HB2 A:LYS29 3.8 0.0 1.0 HB3 A:ARG32 4.0 0.0 1.0 H A:LYS29 4.0 0.0 1.0 CA A:CYS30 4.1 0.0 1.0 CB A:LYS29 4.1 0.0 1.0 HB2 A:ARG32 4.2 0.0 1.0 CA A:CYS60 4.2 0.0 1.0 N A:CYS63 4.2 0.0 1.0 HA A:THR59 4.3 0.0 1.0 H A:ASP31 4.3 0.0 1.0 CA A:CYS63 4.3 0.0 1.0 HB2 A:CYS60 4.4 0.0 1.0 HB2 A:CYS30 4.4 0.0 1.0 C A:LYS29 4.5 0.0 1.0 CB A:ARG32 4.6 0.0 1.0 C A:CYS30 4.6 0.0 1.0 CA A:LYS29 4.7 0.0 1.0 N A:LYS29 4.7 0.0 1.0 N A:ASP31 4.7 0.0 1.0 N A:ARG32 4.7 0.0 1.0 HA A:CYS63 4.7 0.0 1.0 O A:CYS60 4.8 0.0 1.0 CA A:CYS27 4.8 0.0 1.0 CG2 A:THR59 4.8 0.0 1.0 C A:CYS60 4.8 0.0 1.0 HB3 A:ASN62 4.8 0.0 1.0 C A:THR59 4.9 0.0 1.0 HG21 A:THR59 4.9 0.0 1.0 H A:GLY28 5.0 0.0 1.0 HD3 A:LYS29 5.0 0.0 1.0

S.Park, U.Osmers, G.Raman, R.H.Schwantes, M.O.Diaz, J.H.Bushweller. The PHD3 Domain of Mll Acts As A CYP33-Regulated Switch Between Mll-Mediated Activation and Repression. Biochemistry V. 49 6576 2010.
ISSN: ISSN 0006-2960
PubMed: 20677832
DOI: 10.1021/BI1009387