Zinc in PDB 2kje: uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex

All present enzymatic activity of uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex:
2.3.1.48;

The binding sites of Zinc atom in the uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex (pdb code 2kje). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex, PDB code: 2kje:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:0.0 occ:1.00 NE2 A:HIS1782 2.1 0.0 1.0 SG A:CYS1786 2.3 0.0 1.0 SG A:CYS1796 2.3 0.0 1.0 SG A:CYS1791 2.3 0.0 1.0 HB3 A:CYS1791 2.8 0.0 1.0 CD2 A:HIS1782 2.9 0.0 1.0 HD2 A:HIS1782 2.9 0.0 1.0 CB A:CYS1791 2.9 0.0 1.0 HB2 A:CYS1796 3.0 0.0 1.0 HB2 A:CYS1791 3.0 0.0 1.0 HB2 A:CYS1786 3.1 0.0 1.0 CB A:CYS1796 3.1 0.0 1.0 CE1 A:HIS1782 3.3 0.0 1.0 CB A:CYS1786 3.3 0.0 1.0 HB3 A:CYS1796 3.4 0.0 1.0 HE1 A:HIS1782 3.7 0.0 1.0 HB3 A:LEU1793 3.7 0.0 1.0 HZ2 A:LYS1800 3.7 0.0 1.0 HB3 A:CYS1786 3.8 0.0 1.0 CG A:HIS1782 4.1 0.0 1.0 ND1 A:HIS1782 4.3 0.0 1.0 HA A:ALA1783 4.3 0.0 1.0 HZ1 A:LYS1800 4.4 0.0 1.0 CA A:CYS1791 4.4 0.0 1.0 HB2 A:LEU1793 4.5 0.0 1.0 NZ A:LYS1800 4.5 0.0 1.0 HA A:CYS1786 4.6 0.0 1.0 CA A:CYS1796 4.6 0.0 1.0 CB A:LEU1793 4.6 0.0 1.0 CA A:CYS1786 4.6 0.0 1.0 H A:LEU1793 4.6 0.0 1.0 HA A:CYS1796 4.8 0.0 1.0 HG A:LEU1793 4.8 0.0 1.0 HE3 A:LYS1800 4.8 0.0 1.0 HD13 A:LEU1793 4.8 0.0 1.0 HA A:CYS1791 4.8 0.0 1.0 O A:ASN1788 4.9 0.0 1.0 H A:CYS1791 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:0.0 occ:1.00 NE2 A:HIS1805 2.1 0.0 1.0 SG A:CYS1817 2.3 0.0 1.0 SG A:CYS1809 2.3 0.0 1.0 SG A:CYS1820 2.3 0.0 1.0 CD2 A:HIS1805 2.8 0.0 1.0 HD2 A:HIS1805 2.8 0.0 1.0 HB2 A:CYS1809 2.9 0.0 1.0 CB A:CYS1809 3.0 0.0 1.0 H A:CYS1820 3.2 0.0 1.0 HA A:LYS1812 3.3 0.0 1.0 HB3 A:CYS1817 3.3 0.0 1.0 HB A:VAL1819 3.3 0.0 1.0 HB3 A:CYS1809 3.3 0.0 1.0 CB A:CYS1817 3.3 0.0 1.0 CE1 A:HIS1805 3.3 0.0 1.0 H A:LYS1812 3.5 0.0 1.0 HB2 A:CYS1817 3.6 0.0 1.0 HE1 A:HIS1805 3.8 0.0 1.0 CB A:CYS1820 3.9 0.0 1.0 CG A:HIS1805 4.1 0.0 1.0 HB2 A:CYS1820 4.1 0.0 1.0 N A:CYS1820 4.1 0.0 1.0 CA A:LYS1812 4.2 0.0 1.0 HA A:THR1806 4.2 0.0 1.0 N A:LYS1812 4.2 0.0 1.0 ND1 A:HIS1805 4.3 0.0 1.0 CB A:VAL1819 4.4 0.0 1.0 HB3 A:LYS1812 4.4 0.0 1.0 HB3 A:ARG1811 4.4 0.0 1.0 CA A:CYS1809 4.5 0.0 1.0 HA A:CYS1809 4.6 0.0 1.0 H A:VAL1819 4.6 0.0 1.0 CA A:CYS1820 4.6 0.0 1.0 HB3 A:CYS1820 4.7 0.0 1.0 CA A:CYS1817 4.7 0.0 1.0 HG13 A:VAL1819 4.8 0.0 1.0 CB A:LYS1812 4.8 0.0 1.0 H A:ARG1811 4.9 0.0 1.0 HA A:CYS1820 4.9 0.0 1.0

Zinc binding site 3 out of 3 in the uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Structure of Cbp TAZ2 and Adenoviral E1A Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:0.0 occ:1.00 NE2 A:HIS1830 2.1 0.0 1.0 SG A:CYS1839 2.3 0.0 1.0 SG A:CYS1844 2.3 0.0 1.0 SG A:CYS1834 2.3 0.0 1.0 CD2 A:HIS1830 2.8 0.0 1.0 HD2 A:HIS1830 2.9 0.0 1.0 HB2 A:CYS1834 3.1 0.0 1.0 CB A:CYS1834 3.1 0.0 1.0 HB3 A:CYS1834 3.3 0.0 1.0 CE1 A:HIS1830 3.3 0.0 1.0 CB A:CYS1839 3.3 0.0 1.0 HB2 A:CYS1839 3.3 0.0 1.0 HB3 A:CYS1839 3.4 0.0 1.0 CB A:CYS1844 3.6 0.0 1.0 HB2 A:CYS1844 3.6 0.0 1.0 HE1 A:HIS1830 3.7 0.0 1.0 HB3 A:CYS1844 3.8 0.0 1.0 HE3 A:LYS1848 4.0 0.0 1.0 CG A:HIS1830 4.1 0.0 1.0 HB A:VAL1841 4.1 0.0 1.0 HA A:ALA1831 4.1 0.0 1.0 HB3 A:GLU1836 4.2 0.0 1.0 ND1 A:HIS1830 4.3 0.0 1.0 HE2 A:LYS1848 4.4 0.0 1.0 H A:GLU1836 4.6 0.0 1.0 CA A:CYS1834 4.6 0.0 1.0 H A:GLN1835 4.7 0.0 1.0 CE A:LYS1848 4.7 0.0 1.0 HD3 A:LYS1848 4.7 0.0 1.0 CA A:CYS1839 4.7 0.0 1.0 HA A:CYS1834 4.8 0.0 1.0 CA A:CYS1844 4.9 0.0 1.0 H A:VAL1841 4.9 0.0 1.0 HA A:CYS1839 4.9 0.0 1.0 HG21 A:VAL1841 5.0 0.0 1.0 HD2 A:PRO1840 5.0 0.0 1.0 HD21 A:LEU1845 5.0 0.0 1.0

J.C.Ferreon, M.A.Martinez-Yamout, H.J.Dyson, P.E.Wright. Structural Basis For Subversion of Cellular Control Mechanisms By the Adenoviral E1A Oncoprotein. Proc.Natl.Acad.Sci.Usa V. 106 13260 2009.
ISSN: ISSN 0027-8424
PubMed: 19651603
DOI: 10.1073/PNAS.0906770106