Zinc in PDB 2k4d: E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity

The binding sites of Zinc atom in the E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity (pdb code 2k4d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity, PDB code: 2k4d:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:0.0 occ:1.00 SG A:CYS404 1.8 0.0 1.0 SG A:CYS401 1.8 0.0 1.0 SG A:CYS384 1.9 0.0 1.0 SG A:CYS381 1.9 0.0 1.0 HB3 A:CYS381 2.9 0.0 1.0 HB A:ILE383 3.0 0.0 1.0 CB A:CYS381 3.0 0.0 1.0 H A:CYS401 3.2 0.0 1.0 H A:CYS384 3.3 0.0 1.0 CB A:CYS384 3.3 0.0 1.0 HB2 A:ASN387 3.3 0.0 1.0 HB3 A:CYS384 3.4 0.0 1.0 HB2 A:CYS381 3.4 0.0 1.0 CB A:CYS404 3.4 0.0 1.0 HD21 A:ASN387 3.4 0.0 1.0 HB2 A:CYS404 3.5 0.0 1.0 CB A:CYS401 3.6 0.0 1.0 H A:CYS404 3.6 0.0 1.0 HB2 A:SER403 3.7 0.0 1.0 N A:CYS384 3.7 0.0 1.0 HB3 A:CYS401 3.9 0.0 1.0 HD12 A:ILE383 4.0 0.0 1.0 N A:CYS401 4.0 0.0 1.0 CB A:ILE383 4.0 0.0 1.0 HB3 A:CYS404 4.1 0.0 1.0 H A:ILE383 4.1 0.0 1.0 HB2 A:CYS384 4.1 0.0 1.0 N A:CYS404 4.1 0.0 1.0 CA A:CYS384 4.2 0.0 1.0 HB2 A:CYS401 4.2 0.0 1.0 HB2 A:MET400 4.3 0.0 1.0 CA A:CYS401 4.3 0.0 1.0 ND2 A:ASN387 4.3 0.0 1.0 CA A:CYS404 4.4 0.0 1.0 CA A:CYS381 4.4 0.0 1.0 H A:ASN387 4.4 0.0 1.0 CB A:ASN387 4.4 0.0 1.0 H A:ALA385 4.5 0.0 1.0 C A:ILE383 4.5 0.0 1.0 O A:CYS401 4.5 0.0 1.0 HG13 A:ILE383 4.6 0.0 1.0 N A:ILE383 4.6 0.0 1.0 CA A:ILE383 4.6 0.0 1.0 C A:CYS381 4.6 0.0 1.0 O A:CYS381 4.6 0.0 1.0 CG1 A:ILE383 4.7 0.0 1.0 HA A:CYS404 4.7 0.0 1.0 C A:CYS401 4.8 0.0 1.0 CB A:SER403 4.8 0.0 1.0 CD1 A:ILE383 4.8 0.0 1.0 HG23 A:ILE383 4.9 0.0 1.0 CG2 A:ILE383 4.9 0.0 1.0 HG21 A:ILE383 4.9 0.0 1.0 CG A:ASN387 4.9 0.0 1.0 HB3 A:ASN387 4.9 0.0 1.0 HA A:CYS384 4.9 0.0 1.0 HA A:CYS381 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn600 b:0.0 occ:1.00 SG A:CYS396 1.8 0.0 1.0 SG A:CYS421 1.8 0.0 1.0 SG A:CYS416 1.8 0.0 1.0 HD1 A:HIS398 2.6 0.0 1.0 ND1 A:HIS398 2.6 0.0 1.0 CE1 A:HIS398 3.1 0.0 1.0 CG A:HIS398 3.2 0.0 1.0 HB2 A:HIS398 3.3 0.0 1.0 CB A:CYS416 3.3 0.0 1.0 CB A:CYS396 3.3 0.0 1.0 SG A:CYS419 3.4 0.0 1.0 HB2 A:CYS416 3.4 0.0 1.0 HE1 A:HIS398 3.4 0.0 1.0 CB A:CYS421 3.4 0.0 1.0 HB2 A:CYS396 3.5 0.0 1.0 H A:CYS421 3.5 0.0 1.0 HB3 A:CYS396 3.8 0.0 1.0 HB3 A:CYS416 3.8 0.0 1.0 CB A:HIS398 3.8 0.0 1.0 HB2 A:CYS421 3.8 0.0 1.0 H A:CYS416 3.8 0.0 1.0 NE2 A:HIS398 3.9 0.0 1.0 CD2 A:HIS398 3.9 0.0 1.0 O A:CYS421 4.0 0.0 1.0 C A:CYS421 4.0 0.0 1.0 CA A:CYS421 4.1 0.0 1.0 N A:CYS421 4.1 0.0 1.0 HB3 A:CYS421 4.2 0.0 1.0 HG21 A:ILE393 4.2 0.0 1.0 HB3 A:HIS398 4.4 0.0 1.0 H A:HIS398 4.5 0.0 1.0 CA A:CYS396 4.5 0.0 1.0 CA A:CYS416 4.5 0.0 1.0 O A:GLU422 4.5 0.0 1.0 N A:CYS416 4.5 0.0 1.0 HA A:CYS396 4.6 0.0 1.0 HB2 A:CYS419 4.6 0.0 1.0 N A:GLU422 4.7 0.0 1.0 HB A:ILE393 4.7 0.0 1.0 CB A:CYS419 4.7 0.0 1.0 HD2 A:HIS398 4.8 0.0 1.0 HG23 A:ILE393 4.9 0.0 1.0 H A:GLU422 4.9 0.0 1.0 N A:HIS398 5.0 0.0 1.0 CA A:HIS398 5.0 0.0 1.0

A.Huang, R.N.De Jong, H.Wienk, G.S.Winkler, H.T.M.Timmers, R.Boelens. E2-C-Cbl Recognition Is Necessary But Not Sufficient For Ubiquitination Activity J.Mol.Biol. V. 385 507 2009.
ISSN: ISSN 0022-2836
PubMed: 18996392
DOI: 10.1016/J.JMB.2008.10.044