Zinc in PDB 2jzw: How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription
Zinc Binding Sites:
The binding sites of Zinc atom in the How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription
(pdb code 2jzw). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the
How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription, PDB code: 2jzw:
Jump to Zinc binding site number:
1;
2;
Zinc binding site 1 out
of 2 in 2jzw
Go back to
Zinc Binding Sites List in 2jzw
Zinc binding site 1 out
of 2 in the How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn56
b:0.0
occ:1.00
|
NE2
|
A:HIS23
|
2.0
|
0.0
|
1.0
|
SG
|
A:CYS15
|
2.2
|
0.0
|
1.0
|
SG
|
A:CYS28
|
2.2
|
0.0
|
1.0
|
SG
|
A:CYS18
|
2.2
|
0.0
|
1.0
|
HB2
|
A:CYS28
|
2.6
|
0.0
|
1.0
|
CB
|
A:CYS28
|
3.0
|
0.0
|
1.0
|
HB3
|
A:CYS15
|
3.0
|
0.0
|
1.0
|
CB
|
A:CYS15
|
3.0
|
0.0
|
1.0
|
HB3
|
A:CYS18
|
3.1
|
0.0
|
1.0
|
CD2
|
A:HIS23
|
3.1
|
0.0
|
1.0
|
HB2
|
A:CYS15
|
3.1
|
0.0
|
1.0
|
CE1
|
A:HIS23
|
3.1
|
0.0
|
1.0
|
CB
|
A:CYS18
|
3.2
|
0.0
|
1.0
|
HD2
|
A:HIS23
|
3.3
|
0.0
|
1.0
|
HE1
|
A:HIS23
|
3.4
|
0.0
|
1.0
|
HB3
|
A:ASN17
|
3.6
|
0.0
|
1.0
|
HB3
|
A:CYS28
|
3.7
|
0.0
|
1.0
|
H
|
A:CYS18
|
3.7
|
0.0
|
1.0
|
N
|
A:CYS18
|
3.9
|
0.0
|
1.0
|
HA
|
A:CYS28
|
3.9
|
0.0
|
1.0
|
H
|
A:GLY19
|
4.0
|
0.0
|
1.0
|
CA
|
A:CYS18
|
4.0
|
0.0
|
1.0
|
HB2
|
A:CYS18
|
4.1
|
0.0
|
1.0
|
CA
|
A:CYS28
|
4.1
|
0.0
|
1.0
|
HB2
|
A:LYS20
|
4.1
|
0.0
|
1.0
|
CG
|
A:HIS23
|
4.3
|
0.0
|
1.0
|
ND1
|
A:HIS23
|
4.3
|
0.0
|
1.0
|
H
|
A:LYS20
|
4.4
|
0.0
|
1.0
|
HA
|
A:ALA25
|
4.4
|
0.0
|
1.0
|
C
|
A:ASN17
|
4.5
|
0.0
|
1.0
|
CA
|
A:CYS15
|
4.5
|
0.0
|
1.0
|
N
|
A:GLY19
|
4.5
|
0.0
|
1.0
|
O
|
A:LYS20
|
4.6
|
0.0
|
1.0
|
CB
|
A:ASN17
|
4.6
|
0.0
|
1.0
|
C
|
A:CYS18
|
4.6
|
0.0
|
1.0
|
H
|
A:ASN17
|
4.7
|
0.0
|
1.0
|
HB2
|
A:ALA30
|
4.8
|
0.0
|
1.0
|
N
|
A:LYS20
|
4.8
|
0.0
|
1.0
|
HA
|
A:CYS15
|
4.9
|
0.0
|
1.0
|
H
|
A:CYS28
|
4.9
|
0.0
|
1.0
|
N
|
A:CYS28
|
4.9
|
0.0
|
1.0
|
CA
|
A:ASN17
|
5.0
|
0.0
|
1.0
|
CB
|
A:LYS20
|
5.0
|
0.0
|
1.0
|
HA
|
A:CYS18
|
5.0
|
0.0
|
1.0
|
|
Zinc binding site 2 out
of 2 in 2jzw
Go back to
Zinc Binding Sites List in 2jzw
Zinc binding site 2 out
of 2 in the How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn57
b:0.0
occ:1.00
|
NE2
|
A:HIS44
|
2.1
|
0.0
|
1.0
|
SG
|
A:CYS39
|
2.2
|
0.0
|
1.0
|
SG
|
A:CYS36
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS49
|
2.3
|
0.0
|
1.0
|
OE2
|
A:GLU51
|
2.5
|
0.0
|
1.0
|
HB2
|
A:CYS49
|
2.5
|
0.0
|
1.0
|
HB3
|
A:CYS39
|
2.9
|
0.0
|
1.0
|
CB
|
A:CYS49
|
2.9
|
0.0
|
1.0
|
CD2
|
A:HIS44
|
3.1
|
0.0
|
1.0
|
HB3
|
A:CYS49
|
3.1
|
0.0
|
1.0
|
CB
|
A:CYS39
|
3.1
|
0.0
|
1.0
|
CE1
|
A:HIS44
|
3.2
|
0.0
|
1.0
|
CB
|
A:CYS36
|
3.2
|
0.0
|
1.0
|
HB2
|
A:CYS36
|
3.2
|
0.0
|
1.0
|
HB3
|
A:CYS36
|
3.2
|
0.0
|
1.0
|
HD2
|
A:HIS44
|
3.3
|
0.0
|
1.0
|
HE1
|
A:HIS44
|
3.4
|
0.0
|
1.0
|
CD
|
A:GLU51
|
3.5
|
0.0
|
1.0
|
H
|
A:CYS39
|
3.6
|
0.0
|
1.0
|
HB2
|
A:LYS41
|
3.6
|
0.0
|
1.0
|
HB2
|
A:CYS39
|
3.9
|
0.0
|
1.0
|
H
|
A:GLY40
|
4.1
|
0.0
|
1.0
|
OE1
|
A:GLU51
|
4.2
|
0.0
|
1.0
|
CA
|
A:CYS39
|
4.2
|
0.0
|
1.0
|
HG3
|
A:GLU51
|
4.2
|
0.0
|
1.0
|
HD2
|
A:LYS41
|
4.2
|
0.0
|
1.0
|
N
|
A:CYS39
|
4.2
|
0.0
|
1.0
|
CA
|
A:CYS49
|
4.3
|
0.0
|
1.0
|
CG
|
A:HIS44
|
4.3
|
0.0
|
1.0
|
HA
|
A:MET46
|
4.3
|
0.0
|
1.0
|
ND1
|
A:HIS44
|
4.3
|
0.0
|
1.0
|
HA
|
A:CYS49
|
4.4
|
0.0
|
1.0
|
H
|
A:LYS41
|
4.4
|
0.0
|
1.0
|
HB2
|
A:GLU51
|
4.4
|
0.0
|
1.0
|
CG
|
A:GLU51
|
4.4
|
0.0
|
1.0
|
O
|
A:GLN45
|
4.6
|
0.0
|
1.0
|
HE22
|
A:GLN53
|
4.6
|
0.0
|
1.0
|
CB
|
A:LYS41
|
4.6
|
0.0
|
1.0
|
CA
|
A:CYS36
|
4.7
|
0.0
|
1.0
|
N
|
A:GLY40
|
4.7
|
0.0
|
1.0
|
HB3
|
A:LYS38
|
4.7
|
0.0
|
1.0
|
O
|
A:LYS41
|
4.8
|
0.0
|
1.0
|
H
|
A:GLU51
|
4.8
|
0.0
|
1.0
|
C
|
A:CYS39
|
4.8
|
0.0
|
1.0
|
H
|
A:CYS49
|
4.8
|
0.0
|
1.0
|
N
|
A:LYS41
|
4.9
|
0.0
|
1.0
|
HA
|
A:CYS36
|
5.0
|
0.0
|
1.0
|
|
Reference:
S.Bourbigot,
N.Ramalanjaona,
C.Boudier,
G.F.Salgado,
B.P.Roques,
Y.Mely,
S.Bouaziz,
N.Morellet.
How the Hiv-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription. J.Mol.Biol. V. 383 1112 2008.
ISSN: ISSN 0022-2836
PubMed: 18773912
DOI: 10.1016/J.JMB.2008.08.046
Page generated: Thu Oct 17 01:28:47 2024
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