Zinc in PDB 2jvn: Domain C of Human Parp-1

All present enzymatic activity of Domain C of Human Parp-1:
2.4.2.30;

The binding sites of Zinc atom in the Domain C of Human Parp-1 (pdb code 2jvn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Domain C of Human Parp-1, PDB code: 2jvn:

Zinc binding site 1 out of 1 in the Domain C of Human Parp-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Domain C of Human Parp-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn400 b:20.0 occ:1.00 SG A:CYS311 2.2 20.0 1.0 SG A:CYS298 2.3 20.0 1.0 SG A:CYS321 2.3 20.0 1.0 SG A:CYS295 2.3 20.0 1.0 HB3 A:GLU297 2.8 20.0 1.0 HG13 A:VAL323 3.0 20.0 1.0 H A:CYS298 3.1 20.0 1.0 O A:CYS321 3.2 20.0 1.0 HB3 A:CYS295 3.3 20.0 1.0 HG11 A:VAL323 3.3 20.0 1.0 HB3 A:CYS298 3.4 20.0 1.0 CB A:CYS295 3.4 20.0 1.0 HB3 A:CYS321 3.4 20.0 1.0 CB A:CYS298 3.5 20.0 1.0 CB A:CYS321 3.5 20.0 1.0 HB2 A:CYS311 3.5 20.0 1.0 CB A:CYS311 3.6 20.0 1.0 CG1 A:VAL323 3.6 20.0 1.0 H A:GLU297 3.7 20.0 1.0 C A:CYS321 3.7 20.0 1.0 N A:CYS298 3.7 20.0 1.0 HB2 A:CYS295 3.7 20.0 1.0 CB A:GLU297 3.8 20.0 1.0 O A:CYS311 4.0 20.0 1.0 HB2 A:GLU297 4.0 20.0 1.0 HG22 A:VAL323 4.1 20.0 1.0 HA A:MET322 4.1 20.0 1.0 HB3 A:CYS311 4.2 20.0 1.0 CA A:CYS321 4.2 20.0 1.0 CA A:CYS298 4.2 20.0 1.0 H A:VAL323 4.2 20.0 1.0 HB2 A:CYS298 4.3 20.0 1.0 HG12 A:VAL323 4.3 20.0 1.0 HB2 A:CYS321 4.4 20.0 1.0 C A:CYS311 4.4 20.0 1.0 N A:MET322 4.4 20.0 1.0 H A:GLY313 4.4 20.0 1.0 N A:GLU297 4.4 20.0 1.0 CA A:GLU297 4.5 20.0 1.0 HG2 A:GLU297 4.5 20.0 1.0 C A:GLU297 4.5 20.0 1.0 N A:VAL323 4.6 20.0 1.0 HG21 A:VAL323 4.6 20.0 1.0 HD13 A:LEU302 4.6 20.0 1.0 CA A:MET322 4.7 20.0 1.0 CA A:CYS311 4.7 20.0 1.0 CG2 A:VAL323 4.7 20.0 1.0 HA3 A:GLY313 4.7 20.0 1.0 CB A:VAL323 4.7 20.0 1.0 HA3 A:GLY300 4.7 20.0 1.0 N A:GLY313 4.7 20.0 1.0 HA A:THR312 4.7 20.0 1.0 CG A:GLU297 4.8 20.0 1.0 C A:MET322 4.8 20.0 1.0 CA A:CYS295 4.8 20.0 1.0 H A:GLU296 4.9 20.0 1.0 H A:CYS321 4.9 20.0 1.0 H A:GLY300 4.9 20.0 1.0 N A:THR312 4.9 20.0 1.0 HA A:CYS298 4.9 20.0 1.0 H A:MET322 5.0 20.0 1.0

Z.Tao, P.Gao, D.W.Hoffman, H.W.Liu. Domain C of Human Poly(Adp-Ribose) Polymerase-1 Is Important For Enzyme Activity and Contains A Novel Zinc-Ribbon Motif. Biochemistry V. 47 5804 2008.
ISSN: ISSN 0006-2960
PubMed: 18452307
DOI: 10.1021/BI800018A