Zinc in PDB 2hzc: Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit

The structure of Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit, PDB code: 2hzc was solved by K.R.Thickman, E.A.Sickmier, C.L.Kielkopf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.47
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	29.070, 29.070, 184.710, 90.00, 90.00, 90.00
R / Rfree (%)	13.7 / 22.6

The binding sites of Zinc atom in the Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit (pdb code 2hzc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit, PDB code: 2hzc:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:36.2 occ:0.50 O A:HOH317 1.8 18.2 0.5 O A:HOH317 2.0 26.2 0.5 OE1 A:GLU162 2.2 28.6 0.7 OE2 A:GLU162 2.5 46.8 0.3 O A:HOH390 2.7 37.4 1.0 CD A:GLU162 3.3 30.9 0.3 CD A:GLU162 3.3 27.6 0.7 OE1 A:GLU162 3.5 29.4 0.3 O A:HOH458 3.8 56.1 1.0 OE2 A:GLU162 4.0 26.2 0.7 O A:VAL189 4.1 21.0 1.0 O A:HOH350 4.2 26.4 1.0 CG A:GLU162 4.3 29.5 0.7 O A:HOH450 4.4 45.4 1.0 CG A:GLU162 4.6 29.2 0.3 NE2 A:GLN190 4.8 61.8 1.0 CB A:GLU162 4.9 26.9 0.7 CB A:GLU162 4.9 28.1 0.3

Zinc binding site 2 out of 2 in the Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the N-Terminal Rrm of the U2AF Large Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:36.2 occ:1.00 OE2 A:GLU163 1.7 38.8 1.0 OD2 A:ASP167 2.1 28.4 1.0 CG A:ASP167 2.7 20.2 1.0 OD1 A:ASP167 2.8 27.6 1.0 CD A:GLU163 2.8 35.0 1.0 OE1 A:GLU163 3.6 44.3 1.0 CG A:GLU163 3.7 30.7 1.0 O A:HOH398 4.1 52.8 1.0 CB A:ASP167 4.2 17.6 1.0 O A:HOH348 4.9 27.9 1.0 O A:GLU163 4.9 20.1 1.0

K.R.Thickman, E.A.Sickmier, C.L.Kielkopf. Alternative Conformations at the Rna-Binding Surface of the N-Terminal U2AF(65) Rna Recognition Motif. J.Mol.Biol. V. 366 703 2007.
ISSN: ISSN 0022-2836
PubMed: 17188295
DOI: 10.1016/J.JMB.2006.11.077