Zinc in PDB 2faw: Crystal Structure of Papaya Glutaminyl Cyclase

The structure of Crystal Structure of Papaya Glutaminyl Cyclase, PDB code: 2faw was solved by R.Wintjens, H.Belrhali, B.Clantin, M.Azarkan, C.Bompard, D.Baeyens-Volant, Y.Looze, V.Villeret, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.54 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	62.820, 81.200, 108.170, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 20.8

The binding sites of Zinc atom in the Crystal Structure of Papaya Glutaminyl Cyclase (pdb code 2faw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Papaya Glutaminyl Cyclase, PDB code: 2faw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Papaya Glutaminyl Cyclase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Papaya Glutaminyl Cyclase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:19.6 occ:1.00 O A:LEU26 2.2 12.0 1.0 OE1 A:GLU158 2.2 10.9 1.0 O A:ILE211 2.2 12.0 1.0 O A:LEU157 2.3 9.8 1.0 O A:HOH1198 2.3 11.1 1.0 OE1 A:GLU156 2.3 11.6 1.0 OE2 A:GLU156 2.5 11.7 1.0 CD A:GLU156 2.7 10.9 1.0 CD A:GLU158 3.3 12.4 1.0 C A:LEU26 3.3 11.7 1.0 C A:LEU157 3.4 10.1 1.0 C A:ILE211 3.5 11.0 1.0 CB A:GLU158 3.7 11.1 1.0 CA A:GLU158 3.9 10.7 1.0 N A:LEU26 3.9 10.7 1.0 CG A:GLU158 4.0 12.2 1.0 N A:GLU158 4.0 10.4 1.0 CA A:LEU26 4.0 11.0 1.0 O A:HOH1200 4.0 13.6 1.0 N A:ILE211 4.1 10.8 1.0 O A:HOH1371 4.2 12.6 1.0 OE2 A:GLU158 4.2 13.3 1.0 CG A:GLU156 4.2 9.6 1.0 CB A:LEU26 4.3 11.3 1.0 CA A:ILE211 4.3 11.1 1.0 N A:LEU157 4.3 9.8 1.0 O A:LEU112 4.4 13.1 1.0 O A:LEU71 4.4 11.5 1.0 N A:ALA212 4.4 11.0 1.0 N A:VAL27 4.4 12.2 1.0 CA A:ALA212 4.4 12.2 1.0 CB A:ILE211 4.5 11.2 1.0 CA A:LEU157 4.5 9.9 1.0 CA A:VAL27 4.7 13.0 1.0 O A:HOH1201 5.0 15.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Papaya Glutaminyl Cyclase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Papaya Glutaminyl Cyclase within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1002 b:24.6 occ:1.00 OE1 B:GLU158 2.2 14.2 1.0 O B:LEU26 2.2 13.5 1.0 O B:LEU157 2.2 13.8 1.0 O B:ILE211 2.2 13.6 1.0 O B:HOH1191 2.3 15.9 1.0 OE1 B:GLU156 2.3 14.6 1.0 OE2 B:GLU156 2.5 14.4 1.0 CD B:GLU156 2.7 13.3 1.0 C B:LEU157 3.3 13.8 1.0 CD B:GLU158 3.3 15.8 1.0 C B:LEU26 3.4 13.9 1.0 C B:ILE211 3.4 13.5 1.0 CB B:GLU158 3.7 15.7 1.0 CA B:GLU158 3.9 15.6 1.0 N B:LEU26 3.9 14.0 1.0 N B:ILE211 4.0 13.3 1.0 N B:GLU158 4.0 14.1 1.0 CG B:GLU158 4.1 16.5 1.0 CA B:LEU26 4.1 13.5 1.0 O B:HOH1033 4.1 18.8 1.0 O B:HOH1193 4.1 17.5 1.0 CA B:ILE211 4.3 13.4 1.0 CG B:GLU156 4.3 13.1 1.0 N B:LEU157 4.3 13.7 1.0 CB B:LEU26 4.3 13.8 1.0 OE2 B:GLU158 4.3 17.6 1.0 O B:LEU112 4.3 17.1 1.0 O B:LEU71 4.4 16.8 1.0 N B:ALA212 4.4 14.5 1.0 CB B:ILE211 4.4 13.1 1.0 CA B:LEU157 4.4 13.3 1.0 N B:VAL27 4.5 14.8 1.0 CA B:ALA212 4.5 15.1 1.0 CA B:VAL27 4.8 15.5 1.0 O B:HOH1030 5.0 22.8 1.0

R.Wintjens, H.Belrhali, B.Clantin, M.Azarkan, C.Bompard, D.Baeyens-Volant, Y.Looze, V.Villeret. Crystal Structure of Papaya Glutaminyl Cyclase, An Archetype For Plant and Bacterial Glutaminyl Cyclases. J.Mol.Biol. V. 357 457 2006.
ISSN: ISSN 0022-2836
PubMed: 16438985
DOI: 10.1016/J.JMB.2005.12.029