Zinc in PDB 2e73: Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma

All present enzymatic activity of Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma:
2.7.11.13;

The binding sites of Zinc atom in the Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma (pdb code 2e73). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma, PDB code: 2e73:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:0.0 occ:1.00 ND1 A:HIS74 2.0 0.0 1.0 SG A:CYS77 2.2 0.0 1.0 SG A:CYS52 2.2 0.0 1.0 SG A:CYS49 2.4 0.0 1.0 CE1 A:HIS74 2.9 0.0 1.0 H A:HIS74 3.0 0.0 1.0 HB2 A:HIS74 3.0 0.0 1.0 HE1 A:HIS74 3.0 0.0 1.0 CG A:HIS74 3.1 0.0 1.0 H A:CYS52 3.1 0.0 1.0 HB3 A:CYS49 3.2 0.0 1.0 CB A:CYS49 3.3 0.0 1.0 HB2 A:CYS49 3.4 0.0 1.0 HB3 A:CYS52 3.4 0.0 1.0 CB A:CYS77 3.4 0.0 1.0 HB2 A:CYS77 3.4 0.0 1.0 CB A:CYS52 3.5 0.0 1.0 CB A:HIS74 3.6 0.0 1.0 HB3 A:HIS51 3.6 0.0 1.0 HB3 A:CYS77 3.7 0.0 1.0 N A:HIS74 3.8 0.0 1.0 N A:CYS52 3.9 0.0 1.0 NE2 A:HIS74 4.0 0.0 1.0 HB A:VAL73 4.1 0.0 1.0 HB2 A:ASP54 4.1 0.0 1.0 CD2 A:HIS74 4.2 0.0 1.0 HD2 A:HIS51 4.2 0.0 1.0 HB2 A:CYS52 4.3 0.0 1.0 CA A:CYS52 4.3 0.0 1.0 HA A:VAL73 4.3 0.0 1.0 CA A:HIS74 4.3 0.0 1.0 HB3 A:HIS74 4.4 0.0 1.0 H A:ASP54 4.5 0.0 1.0 H A:HIS51 4.6 0.0 1.0 H A:THR53 4.6 0.0 1.0 CB A:HIS51 4.7 0.0 1.0 H A:CYS77 4.7 0.0 1.0 CA A:CYS49 4.7 0.0 1.0 CA A:CYS77 4.8 0.0 1.0 C A:VAL73 4.8 0.0 1.0 HE2 A:HIS74 4.9 0.0 1.0 CA A:VAL73 4.9 0.0 1.0 CD2 A:HIS51 5.0 0.0 1.0 CB A:VAL73 5.0 0.0 1.0 HG3 A:ARG76 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:0.0 occ:1.00 ND1 A:HIS36 2.1 0.0 1.0 SG A:CYS69 2.2 0.0 1.0 SG A:CYS85 2.2 0.0 1.0 SG A:CYS66 2.4 0.0 1.0 HB A:VAL68 2.7 0.0 1.0 H A:CYS69 2.7 0.0 1.0 CE1 A:HIS36 2.9 0.0 1.0 HE1 A:HIS36 3.0 0.0 1.0 HB3 A:HIS36 3.1 0.0 1.0 CG A:HIS36 3.2 0.0 1.0 HB2 A:CYS85 3.4 0.0 1.0 HB3 A:CYS66 3.4 0.0 1.0 HD2 A:PRO86 3.4 0.0 1.0 CB A:CYS66 3.4 0.0 1.0 CB A:CYS85 3.4 0.0 1.0 N A:CYS69 3.5 0.0 1.0 CB A:CYS69 3.5 0.0 1.0 HB2 A:CYS66 3.6 0.0 1.0 HB3 A:CYS69 3.6 0.0 1.0 CB A:HIS36 3.7 0.0 1.0 HA A:CYS85 3.7 0.0 1.0 CB A:VAL68 3.8 0.0 1.0 HB3 A:PHE71 3.9 0.0 1.0 HG13 A:VAL68 3.9 0.0 1.0 CA A:CYS69 4.1 0.0 1.0 NE2 A:HIS36 4.1 0.0 1.0 H A:VAL68 4.2 0.0 1.0 CA A:CYS85 4.2 0.0 1.0 HA A:HIS36 4.2 0.0 1.0 HG22 A:VAL68 4.2 0.0 1.0 H A:LYS37 4.2 0.0 1.0 H A:PHE71 4.3 0.0 1.0 CD2 A:HIS36 4.3 0.0 1.0 HB3 A:CYS85 4.3 0.0 1.0 HB2 A:PHE71 4.3 0.0 1.0 HB2 A:CYS69 4.4 0.0 1.0 HB2 A:ALA88 4.4 0.0 1.0 C A:VAL68 4.4 0.0 1.0 CG1 A:VAL68 4.4 0.0 1.0 CD A:PRO86 4.5 0.0 1.0 CG2 A:VAL68 4.5 0.0 1.0 CA A:VAL68 4.5 0.0 1.0 H A:ALA88 4.5 0.0 1.0 HB2 A:HIS36 4.6 0.0 1.0 CA A:HIS36 4.6 0.0 1.0 CB A:PHE71 4.6 0.0 1.0 HE2 A:PHE83 4.7 0.0 1.0 HB3 A:ALA88 4.7 0.0 1.0 HG21 A:VAL68 4.7 0.0 1.0 N A:VAL68 4.7 0.0 1.0 C A:CYS69 4.8 0.0 1.0 H A:GLY87 4.8 0.0 1.0 HD3 A:PRO86 4.8 0.0 1.0 CA A:CYS66 4.8 0.0 1.0 HE2 A:HIS36 4.9 0.0 1.0 HA A:CYS69 5.0 0.0 1.0

W.Tanabe, S.Suzuki, Y.Muto, M.Inoue, T.Kigawa, T.Terada, M.Shirouzu, S.Yokoyama. Solution Structure of the Phorbol Esters/Diacylglycerol Binding Domain of Protein Kinase C Gamma To Be Published.