Zinc in PDB 2cey: Apo Structure of Siap

The structure of Apo Structure of Siap, PDB code: 2cey was solved by A.Muller, E.Severi, C.Mulligan, A.G.Watts, D.J.Kelly, K.S.Wilson, A.J.Wilkinson, G.H.Thomas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	101.53 / 1.70
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	46.761, 102.508, 202.648, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 23.6

The binding sites of Zinc atom in the Apo Structure of Siap (pdb code 2cey). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Apo Structure of Siap, PDB code: 2cey:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Apo Structure of Siap


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Apo Structure of Siap within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1307 b:41.4 occ:1.00 OD1 A:ASP2 2.2 36.2 1.0 OD2 A:ASP4 2.3 42.4 1.0 OD2 A:ASP2 2.4 39.7 1.0 CG A:ASP2 2.6 41.2 1.0 OD1 A:ASP4 2.6 35.2 1.0 CG A:ASP4 2.8 38.6 1.0 CB A:ASP2 4.1 40.8 1.0 CB A:ASP4 4.3 39.6 1.0 O A:HOH2003 4.4 44.7 1.0 O A:HOH2008 4.6 40.5 1.0 O A:HOH2052 4.7 53.0 1.0 N A:ASP4 4.8 37.9 1.0 C A:ASP2 4.8 41.4 1.0 CA A:ASP2 4.9 41.8 1.0 O A:HOH2007 5.0 47.9 1.0

Zinc binding site 2 out of 3 in the Apo Structure of Siap


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Apo Structure of Siap within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1308 b:35.5 occ:1.00 OE2 A:GLU101 1.9 36.6 1.0 OD2 A:ASP105 2.2 37.4 1.0 CG A:ASP105 2.8 35.4 1.0 OD1 A:ASP105 2.8 32.7 1.0 CD A:GLU101 3.0 37.1 1.0 CG A:GLU101 3.4 38.4 1.0 O A:HOH2131 4.2 49.8 1.0 OE1 A:GLU101 4.2 40.9 1.0 CB A:ASP105 4.2 36.1 1.0 O A:HOH2139 4.2 40.9 1.0 NZ A:LYS108 4.3 45.1 1.0 O A:GLU101 4.9 35.3 1.0 CB A:GLU101 5.0 37.1 1.0 CE A:LYS108 5.0 45.3 1.0

Zinc binding site 3 out of 3 in the Apo Structure of Siap


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Apo Structure of Siap within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1309 b:32.6 occ:0.50 NE2 A:HIS269 2.1 38.0 1.0 CD2 A:HIS269 3.1 37.1 1.0 CE1 A:HIS269 3.1 34.1 1.0 ND1 A:HIS269 4.1 38.8 1.0 CG A:HIS269 4.2 39.4 1.0 O A:HOH2117 4.7 38.9 1.0 CG2 A:ILE267 4.9 33.9 1.0 O A:HOH2045 5.0 44.5 1.0

A.Muller, E.Severi, C.Mulligan, A.G.Watts, D.J.Kelly, K.S.Wilson, A.J.Wilkinson, G.H.Thomas. Conservation of Structure and Mechanism in Primary and Secondary Transporters Exemplified By Siap, A Sialic Acid Binding Virulence Factor From Haemophilus Influenzae J.Biol.Chem. V. 281 22212 2006.
ISSN: ISSN 0021-9258
PubMed: 16702222
DOI: 10.1074/JBC.M603463200