Atomistry » Zinc » PDB 2c7a-2cij » 2c7a
Atomistry »
  Zinc »
    PDB 2c7a-2cij »
      2c7a »

Zinc in PDB 2c7a: Structure of the Progesterone Receptor-Dna Complex

Protein crystallography data

The structure of Structure of the Progesterone Receptor-Dna Complex, PDB code: 2c7a was solved by S.C.Roemer, D.C.Donham, L.Sherman, V.H.Pon, D.P.Edwards, M.E.A.Churchill, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.5
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 39.530, 107.850, 111.960, 90.00, 90.00, 90.00
R / Rfree (%) 19.8 / 24.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of the Progesterone Receptor-Dna Complex (pdb code 2c7a). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of the Progesterone Receptor-Dna Complex, PDB code: 2c7a:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 2c7a

Go back to Zinc Binding Sites List in 2c7a
Zinc binding site 1 out of 4 in the Structure of the Progesterone Receptor-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Progesterone Receptor-Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1641

b:34.1
occ:1.00
SG A:CYS570 2.3 31.6 1.0
SG A:CYS567 2.3 35.1 1.0
SG A:CYS587 2.3 31.3 1.0
SG A:CYS584 2.3 32.5 1.0
CB A:CYS567 3.3 37.0 1.0
CB A:CYS587 3.3 31.4 1.0
CB A:CYS570 3.4 33.3 1.0
CB A:CYS584 3.4 33.3 1.0
N A:CYS570 3.7 32.3 1.0
N A:CYS584 3.9 33.3 1.0
CA A:CYS570 4.1 33.8 1.0
N A:CYS587 4.2 31.2 1.0
CA A:CYS584 4.2 33.7 1.0
OG A:SER586 4.2 31.8 1.0
NH1 A:ARG616 4.3 35.5 1.0
CA A:CYS587 4.4 31.6 1.0
CB A:ILE569 4.4 31.9 1.0
CB A:ASP572 4.5 41.8 1.0
C A:ILE569 4.7 32.5 1.0
C A:CYS570 4.7 35.2 1.0
CA A:CYS567 4.7 37.5 1.0
O A:CYS584 4.7 34.3 1.0
C A:CYS584 4.8 34.3 1.0
N A:GLY571 4.8 36.5 1.0
NH2 A:ARG623 4.8 35.6 1.0
N A:ASP572 4.9 39.8 1.0
CD A:ARG616 4.9 33.2 1.0
CA A:ILE569 4.9 31.9 1.0
N A:ILE569 5.0 32.7 1.0
CB A:THR583 5.0 33.0 1.0

Zinc binding site 2 out of 4 in 2c7a

Go back to Zinc Binding Sites List in 2c7a
Zinc binding site 2 out of 4 in the Structure of the Progesterone Receptor-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Progesterone Receptor-Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1642

b:27.0
occ:1.00
SG A:CYS619 2.3 29.6 1.0
SG A:CYS622 2.3 22.7 1.0
SG A:CYS603 2.3 27.1 1.0
SG A:CYS609 2.3 25.3 1.0
CB A:CYS603 3.2 27.7 1.0
CB A:CYS609 3.2 25.6 1.0
CB A:CYS622 3.3 26.1 1.0
CB A:CYS619 3.4 27.8 1.0
O A:HOH2026 4.0 23.2 1.0
CA A:CYS603 4.0 28.2 1.0
N A:CYS609 4.0 25.4 1.0
N A:CYS622 4.1 26.4 1.0
CA A:CYS609 4.2 25.4 1.0
O A:HOH2024 4.3 30.4 1.0
CA A:CYS622 4.3 26.3 1.0
O A:HOH2029 4.4 25.7 1.0
CA A:ASN607 4.5 29.6 1.0
N A:ASN607 4.5 29.0 1.0
O B:HOH2007 4.5 23.9 1.0
N A:ASP608 4.6 28.8 1.0
C A:CYS603 4.8 29.0 1.0
CA A:CYS619 4.8 28.2 1.0
C A:ASN607 4.9 29.2 1.0
O A:CYS619 4.9 28.3 1.0
N A:ALA604 4.9 29.2 1.0
N A:GLY605 4.9 28.6 1.0
CB A:ALA621 5.0 24.1 1.0

Zinc binding site 3 out of 4 in 2c7a

Go back to Zinc Binding Sites List in 2c7a
Zinc binding site 3 out of 4 in the Structure of the Progesterone Receptor-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of the Progesterone Receptor-Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1639

b:37.5
occ:1.00
SG B:CYS570 2.3 37.0 1.0
SG B:CYS587 2.3 34.9 1.0
SG B:CYS584 2.3 37.8 1.0
SG B:CYS567 2.3 38.8 1.0
CB B:CYS570 3.3 36.1 1.0
CB B:CYS587 3.3 35.4 1.0
CB B:CYS567 3.4 42.1 1.0
CB B:CYS584 3.4 38.5 1.0
N B:CYS570 3.7 35.2 1.0
N B:CYS584 3.9 40.3 1.0
CA B:CYS570 4.0 35.8 1.0
N B:CYS587 4.1 35.4 1.0
CA B:CYS584 4.3 39.5 1.0
CB B:ILE569 4.3 34.5 1.0
CA B:CYS587 4.4 35.6 1.0
OG B:SER586 4.4 34.3 1.0
CB B:ASP572 4.5 43.1 1.0
NH1 B:ARG616 4.6 33.2 1.0
C B:ILE569 4.7 35.8 1.0
C B:CYS570 4.8 36.2 1.0
N B:GLY571 4.8 37.5 1.0
NH2 B:ARG623 4.8 35.1 1.0
CA B:CYS567 4.9 42.5 1.0
C B:CYS584 4.9 39.4 1.0
CA B:ILE569 4.9 35.1 1.0
N B:ASP572 4.9 41.0 1.0
O B:CYS584 4.9 39.7 1.0
CG1 B:ILE569 5.0 32.7 1.0

Zinc binding site 4 out of 4 in 2c7a

Go back to Zinc Binding Sites List in 2c7a
Zinc binding site 4 out of 4 in the Structure of the Progesterone Receptor-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of the Progesterone Receptor-Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1640

b:30.2
occ:1.00
SG B:CYS609 2.3 27.0 1.0
SG B:CYS603 2.3 29.1 1.0
SG B:CYS622 2.3 28.3 1.0
SG B:CYS619 2.3 29.4 1.0
CB B:CYS603 3.3 28.8 1.0
CB B:CYS609 3.3 30.7 1.0
CB B:CYS619 3.3 28.4 1.0
CB B:CYS622 3.4 29.8 1.0
CA B:CYS603 4.0 30.4 1.0
N B:CYS609 4.1 32.6 1.0
O B:HOH2021 4.2 25.7 1.0
N B:CYS622 4.3 28.2 1.0
O B:HOH2043 4.3 54.0 1.0
CA B:ASN607 4.3 35.4 1.0
CA B:CYS609 4.3 31.0 1.0
CA B:CYS622 4.4 29.2 1.0
N B:ASN607 4.4 35.8 1.0
N B:ASP608 4.5 35.2 1.0
C B:ASN607 4.7 34.9 1.0
CA B:CYS619 4.7 28.8 1.0
N B:ALA604 4.8 31.0 1.0
C B:CYS603 4.8 30.6 1.0
N B:GLY605 4.9 31.7 1.0

Reference:

S.C.Roemer, D.C.Donham, L.Sherman, V.H.Pon, D.P.Edwards, M.E.A.Churchill. Structure of the Progesterone Receptor- Deoxyribonucleic Acid Complex: Novel Interactions Required For Binding to Half-Site Response Elements. Mol.Endocrinol. V. 20 3042 2006.
ISSN: ISSN 0888-8809
PubMed: 16931575
DOI: 10.1210/ME.2005-0511
Page generated: Wed Oct 16 22:13:45 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy